Evidence map›Paper›PMID 36655447›Full record

ArticleThe Eurasian journal of medicine2022

An Overview of Ischemia-Reperfusion Injury: Review on Oxidative Stress and Inflammatory Response.

Mustafa Can Güler, Ayhan Tanyeli, Fazile Nur Ekinci Akdemir, Ersen Eraslan, Saime Özbek Şebin, Derya Güzel Erdoğan, Tuncer Nacar

Open access · diamondAbstract read
In one paragraph

Article in The Eurasian journal of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 22 citations in OpenAlex.

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  15. Nephroprotective effects of ethanol leaf extract ofResearch in pharmaceutical sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mustafa Can GülerDepartment of Physiology, Atatürk University Faculty of Medicine, Erzurum, Turkey.
Ayhan TanyeliDepartment of Physiology, Atatürk University Faculty of Medicine, Erzurum, Turkey.
Fazile Nur Ekinci AkdemirDepartment of Nutrition and Dietetics, Ağrı İbrahim Çeçen University Faculty of Medicine, Ağrı, Turkey.
Ersen EraslanDepartment of Physiology, Yozgat Bozok University Faculty of Medicine, Yozgat, Turkey.
Saime Özbek ŞebinDepartment of Physiology, Atatürk University Faculty of Medicine, Erzurum, Turkey.
Derya Güzel ErdoğanDepartment of Physiology, Sakarya University Faculty of Medicine, Sakarya, Turkey.
Tuncer NacarDepartment of Physiology, Yüksek İhtisas University Faculty of Medicine, Ankara, Turkey.
Atatürk University · TRBozok Universitesi · TRSakarya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemia-reperfusion is a common health problem leading to several health conditions. The pathophysiology of ischemia-reperfusion is quite complex. Oxidative stress and inflammatory response contribute to ischemia-reperfusion mechanisms. Various parameters like proinflammatory cytokines, reactive oxygen species, occur during ischemia-reperfusion . There are several ways to investigate these values through biochemical and histopathologic findings. Malondialdehyde, glutathione, myeloperoxidase, superoxide dismutase, interleukin 6, interleukin 1β, tumor necrosis factor alpha, caspase-3, nuclear factor-kappa β, and LC3B (microtubu le-associated protein light chain 3, LC3) can be evaluated among these indicators.

Identifiers

PMID36655447
PMCPMC11163358
OpenAlexW4317212717

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.