ArticleERJ open research2022
The demographics, clinical characteristics and quality of life of patients with chronic cough from the Isala Cough Clinic in the Netherlands.
Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 18 citations in OpenAlex.
- Trial
- Challenges and Burdens in Refractory Chronic Cough: Patients' and Physicians' Perspectives.Pulmonary therapy · 2026Review
- Health-Related Quality of Life in Chronic Cough: A Comparative Analysis With Other Chronic Diseases.Allergy, asthma & immunology research · 2026Article
- Association Between Extrapulmonary Chronic Cough and Psychiatric Comorbidities.The Laryngoscope · 2026Article
- Quality of life associated with chronic cough in the multinational Burden of Obstructive Lung Disease study: a cross-sectional study.ERJ open research · 2025Article
- The NEuroCOUGH Chronic Cough Registry: a protocol for a pan-European observational study.ERJ open research · 2025Article
- Cough frequency has a high daily variation in patients with chronic cough.ERJ open research · 2025Article
- Article
- An observational study to understand burden and cost of care in adults diagnosed with refractory chronic cough (RCC) or unexplained chronic cough (UCC).Respiratory research · 2024Observational
- Severity grading of the Leicester Cough Questionnaire in chronic cough.ERJ open research · 2024Article
- Coughing our guts up: how do we diagnose reflux cough?ERJ open research · 2024Article
- Patient satisfaction with the management of refractory and unexplained chronic cough in Canada: Results from a national survey.PloS one · 2024Article
- Consensus goals and standards for specialist cough clinics: the NEUROCOUGH international Delphi study.ERJ open research · 2023Article
- New Insights Into Refractory Chronic Cough and Unexplained Chronic Cough: A 6-Year Ambispective Cohort Study.Allergy, asthma & immunology research · 2023Article
- Airway disease: a confusion inside an enigma.ERJ open research · 2022Article
- A retrospective study to understand the journey and health status of patients with unexplained or refractory chronic cough in the Netherlands.Chronic respiratory diseaseObservational
- Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Chronic cough affects ∼10% of the population and adversely impacts quality of life. This retrospective observational cohort study aimed to identify the demographics, clinical characteristics and quality of life of the chronic cough population in a Dutch chronic cough clinic, at baseline and following treatment at 6 months. Patients were categorised based on the underlying phenotype and response to treatment. Methods: Retrospective data on 2397 patients who were diagnosed according to standard guidelines of the American College of Chest Physicians were analysed. Quality of life was captured Results: Mean patient age was 59 years; 62.5% of the patients were female; and 69.1% had at least one underlying phenotype associated with chronic cough. Of the latter, 52.1% had bronchial hyperresponsiveness/airflow limitation, 33.3% had airway reflux and 20.1% had upper airway cough syndrome. 46% of patients with a phenotype, and 51% without, experienced no improvement in their quality of life or still had significant cough remaining after 6 months. Of patients with available quality-of-life data, 37.5% were categorised as having refractory chronic cough, and 9.5% were categorised as unexplained chronic cough. Discussion: This study highlights the poor quality-of-life outcomes in patients with chronic cough, despite interventions to treat underlying conditions, and indicates a need to manage chronic cough irrespective of phenotype.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.