Evidence map›Paper›PMID 36655216›Full record

ArticlePhysics and imaging in radiation oncology2023

Quality assurance process within the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial for the fusion of electroanatomical mapping and radiotherapy planning imaging data in cardiac radioablation.

Michael Mayinger, Judit Boda-Heggemann, Felix Mehrhof, David Krug, Stephan Hohmann, Jingyang Xie, Stefanie Ehrbar, Boldizsar Kovacs, Roland Merten, Melanie Grehn and 13 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03867747 (Radiosurgery for the Treatment of Refractory Ventricular Extrasystoles and Tachycardias), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03867747 nacompletednot on this map

Radiosurgery for the Treatment of Refractory Ventricular Extrasystoles and Tachycardias (RAVENTA)

TypeinterventionalSponsorUniversity Hospital Schleswig-HolsteinRan2019 to 2024Enrolled20ConditionsVentricular TachycardiaArmsCardiac Radiosurgery
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Development of a prospective clinical workflow for proton beam therapy of ventricular tachycardia.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  5. Excellent interobserver agreement and steep learning curve for target volume delineation for stereotactic arrhythmia radioablation using a commercial software.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  6. Article
  7. Patient selection, ventricular tachycardia substrate delineation, and data transfer for stereotactic arrhythmia radioablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  8. Article
  9. Article
  10. Radiation therapy for ventricular arrhythmias.Journal of medical imaging and radiation oncology · 2024
    Review
  11. Stereotactic arrhythmia radioablation and its implications for modern cardiac electrophysiology: results of an EHRA survey.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  12. Article
  13. Cardiac radiotherapy transiently alters left ventricular electrical properties and induces cardiomyocyte-specific ventricular substrate changes in heart failure.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Radiosurgery for ventricular tachycardia (RAVENTA): interim analysis of a multicenter multiplatform feasibility trial.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 8 institutions in 2 countries.

Michael MayingerDepartment of Radiation Oncology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
Judit Boda-HeggemannDepartment of Radiation Oncology, University Medicine Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Felix MehrhofDepartment of Radiation Oncology, Charité University Medicine Berlin, Berlin, Germany.
David KrugDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Kiel, Germany.
Stephan HohmannDepartment of Cardiology and Angiology, Hannover Heart Rhythm Center, Hannover Medical School, Hannover, Germany.
Jingyang XieInstitute for Robotics and Cognitive Systems, Univesity of Lübeck, Lübeck, Germany.
Stefanie EhrbarDepartment of Radiation Oncology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
Boldizsar KovacsDepartment of Cardiology, University Heart Center Zurich, University Hospital Zurich, Switzerland.
Roland MertenDepartment of Radiotherapy, Hannover Medical School, Hannover, Germany.
Melanie GrehnDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Kiel, Germany.
Adrian ZamanDepartment of Internal Medicine III, Section for Electrophysiology und Rhythmology, University Medical Center Schleswig-Holstein, Kiel, Germany.
Jens FleckensteinDepartment of Radiation Oncology, University Medicine Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Lena KaestnerDepartment of Radiation Oncology, University Medicine Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Daniel BuergyDepartment of Radiation Oncology, University Medicine Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Boris RudicMedizinische Klinik I, Abteilung für Elektrophysiologie und Rhythmologie, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Anne KlugeDepartment of Radiation Oncology, Charité University Medicine Berlin, Berlin, Germany.
Leif-Hendrik BoldtDepartment of Cardiology, University Medicine Berlin, Campus Virchow-Klinikum, Berlin, Germany.
Jürgen DunstDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Kiel, Germany.
Hendrik BonnemeierDepartment of Internal Medicine III, Section for Electrophysiology und Rhythmology, University Medical Center Schleswig-Holstein, Kiel, Germany.
Ardan M SagunerDepartment of Cardiology, University Heart Center Zurich, University Hospital Zurich, Switzerland.
Nicolaus AndratschkeDepartment of Radiation Oncology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
Oliver BlanckDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Kiel, Germany.
Achim SchweikardInstitute for Robotics and Cognitive Systems, Univesity of Lübeck, Lübeck, Germany.
University Hospital of Zurich · CHUniversity Hospital Heidelberg · DECharité - Universitätsmedizin Berlin · DEMedizinische Hochschule Hannover · DEUniversity Hospital Schleswig-Holstein · DEUniversity Medical Centre Mannheim · DEUniversity of Lübeck · DEVivantes Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel quality assurance process for electroanatomical mapping (EAM)-to-radiotherapy planning imaging (RTPI) target transport was assessed within the multi-center multi-platform framework of the RAdiosurgery for VENtricular TAchycardia (RAVENTA) trial. A stand-alone software (CARDIO-RT) was developed to enable platform independent registration of EAM and RTPI of the left ventricle (LV), based on pre-generated radiotherapy contours (RTC). LV-RTC were automatically segmented into the American-Heart-Association 17-segment-model and a manual 3D-3D method based on EAM 3D-geometry data and a semi-automated 2D-3D method based on EAM screenshot projections were developed. The quality of substrate transfer was evaluated in five clinical cases and the structural analyses showed substantial differences between manual target transfer and target transport using CARDIO-RT.

Indexed as

Cardiac radioablationCARDIO-RTElectroanatomical mappingQuality assuranceRadiotherapy planning

Identifiers

PMID36655216
PMCPMC9841340
OpenAlexW4312220628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.