Evidence map›Paper›PMID 36655215›Full record

ArticlePhysics and imaging in radiation oncology2023

Towards interactive deep-learning for tumour segmentation in head and neck cancer radiotherapy.

Zixiang Wei, Jintao Ren, Stine Sofia Korreman, Jasper Nijkamp

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Interactive AI annotation of medical images in a virtual reality environment.International journal of computer assisted radiology and surgery · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Gradient Map-Assisted Head and Neck Tumor Segmentation: A Pre-RT to Mid-RT Approach in MRI-Guided Radiotherapy.Head and Neck Tumor Segmentation for MR-Guided Applications : First MICCAI Challenge, HNTS-MRG 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, October 17, 2024, proceedings · 2025
    Article
  7. UMamba Adjustment: Advancing GTV Segmentation for Head and Neck Cancer in MRI-Guided RT with UMamba and NnU-Net ResEnc Planner.Head and Neck Tumor Segmentation for MR-Guided Applications : First MICCAI Challenge, HNTS-MRG 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, October 17, 2024, proceedings · 2025
    Article
  8. Deep learning-assisted interactive contouring of lung cancer: Impact on contouring time and consistency.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zixiang WeiAarhus University, Department of Clinical Medicine, Aarhus, Denmark.
Jintao RenAarhus University, Department of Clinical Medicine, Aarhus, Denmark.
Stine Sofia KorremanAarhus University, Department of Clinical Medicine, Aarhus, Denmark.
Jasper NijkampAarhus University, Department of Clinical Medicine, Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: With deep-learning, gross tumour volume (GTV) auto-segmentation has substantially been improved, but still substantial manual corrections are needed. With interactive deep-learning (iDL), manual corrections can be used to update a deep-learning tool while delineating, minimising the input to achieve acceptable segmentations. We present an iDL tool for GTV segmentation that took annotated slices as input and simulated its performance on a head and neck cancer (HNC) dataset. Materials and methods: Multimodal image data of 204 HNC patients with clinical tumour and lymph node GTV delineations were used. A baseline convolutional neural network (CNN) was trained (n = 107 training, n = 22 validation) and tested (n = 24). Subsequently, user input was simulated on initial test set by replacing one or more of predicted slices with ground truth delineation, followed by re-training the CNN. The objective was to optimise re-training parameters and simulate slice selection scenarios while limiting annotations to maximally-five slices. The remaining 51 patients were used as an independent test set, where Dice similarity coefficient (DSC), mean surface distance (MSD), and 95% Hausdorff distance (HD Results: Median segmentation accuracy at baseline was DSC = 0.65, MSD = 4.3 mm, HD Conclusions: The presented iDL tool achieved substantial segmentation improvement with only five annotated slices.

Indexed as

Convolutional neural networkHead and neck cancerInteractive deep-learningRadiotherapyTumour segmentation

Identifiers

PMID36655215
PMCPMC9841279

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.