Evidence map›Paper›PMID 36655213›Full record

ArticlePhysics and imaging in radiation oncology2023

View-sharing for 4D magnetic resonance imaging with randomized projection-encoding enables improvements of respiratory motion imaging for treatment planning in abdominothoracic radiotherapy.

Ergys Subashi, Li Feng, Yilin Liu, Scott Robertson, Paul Segars, Bastiaan Driehuys, Christopher R Kelsey, Fang-Fang Yin, Ricardo Otazo, Jing Cai

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ergys SubashiDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Li FengBiomedical Engineering and Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Yilin LiuDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Scott RobertsonMedical Physics Graduate Program, Duke University Medical Center, Durham, NC, United States.
Paul SegarsMedical Physics Graduate Program, Duke University Medical Center, Durham, NC, United States.
Bastiaan DriehuysMedical Physics Graduate Program, Duke University Medical Center, Durham, NC, United States.
Christopher R KelseyDepartment of Radiation Oncology, Duke University Medical Center, Durham, NC, United States.
Fang-Fang YinMedical Physics Graduate Program, Duke University Medical Center, Durham, NC, United States.
Ricardo OtazoDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Jing CaiDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
Toward precision radiotherapy: Physiological modeling of respiratory motion based on ultra-quality 4D-MRIR01CA226899 · NCI · UNIVERSITY OF VIRGINIA · PI CAI, JING, MILLER, G. WILSON · 2019 to 2023
$2.2M
Rapid Motion-Robust and Easy-to-Use Dynamic Contrast-Enhanced MRI for Liver Perfusion QuantificationR01EB030549 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FENG, LI · 2021 to 2024
$1.7M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA226899NIBIB NIH HHS P41 EB017183NIBIB NIH HHS R01 EB030549
6 · The paper itself

Abstract

Background and Purpose: The accuracy and precision of radiation therapy are dependent on the characterization of organ-at-risk and target motion. This work aims to demonstrate a 4D magnetic resonance imaging (MRI) method for improving spatial and temporal resolution in respiratory motion imaging for treatment planning in abdominothoracic radiotherapy. Materials and Methods: The spatial and temporal resolution of phase-resolved respiratory imaging is improved by considering a novel sampling function based on quasi-random projection-encoding and peripheral k-space view-sharing. The respiratory signal is determined directly from k-space, obviating the need for an external surrogate marker. The average breathing curve is used to optimize spatial resolution and temporal blurring by limiting the extent of data sharing in the Fourier domain. Improvements in image quality are characterized by evaluating changes in signal-to-noise ratio (SNR), resolution, target detection, and level of artifact. The method is validated in simulations, in a dynamic phantom, and in-vivo imaging. Results: Sharing of high-frequency k-space data, driven by the average breathing curve, improves spatial resolution and reduces artifacts. Although equal sharing of k-space data improves resolution and SNR in stationary features, phases with large temporal changes accumulate significant artifacts due to averaging of high frequency features. In the absence of view-sharing, no averaging and detection artifacts are observed while spatial resolution is degraded. Conclusions: The use of a quasi-random sampling function, with view-sharing driven by the average breathing curve, provides a feasible method for self-navigated 4D-MRI at improved spatial resolution.

Indexed as

4D-MRIProjection-encodingRespiratory imagingView-sharing

Identifiers

PMID36655213
PMCPMC9841273

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.