Evidence map›Paper›PMID 36655100›Full record

ArticleFood science & nutrition2023

Beneficial effects of arthrocen on neuroinflammation and behavior like depression in stroke in a murine model.

Ramin Goudarzi, Golnaz Zamanian, Zahra Seyyedian, Partow Mirzaee Saffari, Ahmad Reza Dehpour, Alireza Partoazar

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ramin GoudarziDivision of Research and Development, Pharmin USA LLC San Jose California USA.
Golnaz ZamanianDepartment of Pharmacology, School of Medicine Tehran University of Medical Sciences Tehran Iran.
Zahra SeyyedianDepartment of Pharmacology, School of Medicine Tehran University of Medical Sciences Tehran Iran.
Partow Mirzaee SaffariDepartment of Pharmacology, School of Medicine Tehran University of Medical Sciences Tehran Iran.
Ahmad Reza DehpourDepartment of Pharmacology, School of Medicine Tehran University of Medical Sciences Tehran Iran.
Alireza PartoazarDepartment of Pharmacology, School of Medicine Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-8499-4932
Tehran University of Medical Sciences · IRTeikoku Pharma (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is a considerable reason for death, disability, socioeconomic loss, and depression in the world. Notably, many attempts to the reduction of the complications of poststroke injuries like depression have failed so far. In this study, we aimed to evaluate the anti-inflammatory effect of arthrocen, avocado/soybean unsaponifiables (ASU), in the poststroke injuries like depression improvement in a mice model. We examined the antidepressant-like effect of arthrocen using the forced swimming test and tail suspension test in mice subjected to stroke. Furthermore, immunohistochemistry of proinflammatory cytokines, IL-10 and TNF-α, and neural cell count were performed in the ischemic brain hippocampus of mice. Oral arthrocen reduced significantly (

Indexed as

animal modelarthrocenavocado/soybean unsaponifiablesbioactive naturalbrain ischemiaherbalROCEN

Identifiers

PMID36655100
PMCPMC9834816
OpenAlexW4302027645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.