Evidence map›Paper›PMID 36655091›Full record

ArticleFood science & nutrition2023

Linalool attenuated ischemic injury in PC12 cells through inhibition of caspase-3 and caspase-9 during apoptosis.

Azar Hosseini, Elham Pourheidar, Arezoo Rajabian, Elham Asadpour, Hossein Hosseinzadeh, Hamid Reza Sadeghnia

Abstract read
In one paragraph

Article in Food science & nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Azar HosseiniPharmacological Research Center of Medicinal Plants Mashhad University of Medical Sciences Mashhad Iran.
Elham PourheidarDepartment of Intensive Care Unit Hazrat Rasul akram Hospital Iran University of Medical Sciences Tehran Iran.
Arezoo RajabianDepartment of Internal Medicine, Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0003-3765-7463
Elham AsadpourAnesthesiology and Critical Care Research Center Shiraz University of Medical Sciences Shiraz Iran.
Hossein HosseinzadehPharmaceutical Research Center Pharmaceutical Technology Institute Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-7755-2204
Hamid Reza SadeghniaPharmacological Research Center of Medicinal Plants Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-3228-6897

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have indicated the pharmacological properties of linalool, a volatile terpene alcohol found in many flowers and spice plants, including anti-nociceptive, anti-inflammatory, and neuroprotective activities. The aim of this study was to explore the mechanisms of neuroprotection provided by (±) linalool and its enantiomer, (

Indexed as

ischemia(±) linalooloxygen–glucose deprivation/reoxygenation(R)‐(−) linalool

Identifiers

PMID36655091
PMCPMC9834854

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.