Evidence map›Paper›PMID 36654962›Full record

ArticlePhotoacoustics2023

A high-sensitivity high-resolution intravascular photoacoustic catheter through mode cleaning in a graded-index fiber.

Yuhao Yuan, Guangju Zhang, Yuqi Chen, Hongli Ni, Mingsheng Li, Michael Sturek, Ji-Xin Cheng

Open access · goldAbstract read
In one paragraph

Article in Photoacoustics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yuhao YuanDepartment of Electrical and Computer Engineering, Boston University, Boston, MA 02215, USA.
Guangju ZhangDepartment of Electrical and Computer Engineering, Boston University, Boston, MA 02215, USA.
Yuqi ChenDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Hongli NiDepartment of Electrical and Computer Engineering, Boston University, Boston, MA 02215, USA.
Mingsheng LiDepartment of Electrical and Computer Engineering, Boston University, Boston, MA 02215, USA.
Michael SturekCorVus Biomedical, LLC and CorVus Foundation, Inc, Crawfordsville, IN 47933, USA.
Ji-Xin ChengDepartment of Electrical and Computer Engineering, Boston University, Boston, MA 02215, USA.
Boston University · US

Funding

Sensing Vulnerable Plaque in vivo by an All-optical Intravascular Ultrasound and Photoacoustic CatheterR01HL125385 · NHLBI · PURDUE UNIVERSITY · PI CHENG, JI-XIN · 2015 to 2023
$4.6M
NHLBI NIH HHS R01 HL125385
6 · The paper itself

Abstract

Intravascular photoacoustic imaging has been developed to evaluate the possibility of plaque rupture in atherosclerosis by high spatial resolution imaging of lipid. However, the detection sensitivity and spatial resolution are compromised by the poor focusing caused by a multimode fiber. In this work, we report an intravascular photoacoustic catheter with mode self-cleaning in a graded-index fiber to improve the beam quality and the sensitivity for lipid detection. Compared with the higher-order modes in a step-index multimode fiber, the lower-order modes generated by the self-cleaning effect in the graded-index fiber greatly enhanced the photoacoustic spatial resolution and detection sensitivity. The dominant ringing artifact caused by laser absorption of the ultrasound transducer was further reduced by using stripe suppression. A lipid plaque mimicking phantom was imaged for evaluation. Lipid particles with a small diameter of 75.7 µm were clearly observed.

Indexed as

AtherosclerosisGraded-index fiberIntravascularLipid plaquePhotoacoustic imagingSelf-cleaning

Identifiers

PMID36654962
PMCPMC9841289
OpenAlexW4313655190

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.