Evidence map›Paper›PMID 36654837›Full record

Article3D printing and additive manufacturing2021

Additive Fabrication of a Vascular 3D Phantom for Stereotactic Radiosurgery of Arteriovenous Malformations.

Elisa Legnani, Pasqualina Gallo, Federico Pezzotta, Francesco Padelli, Giuseppe Faragò, Andrea Gioppo, Lorenzo Gentili, Elena De Martin, Maria Luisa Fumagalli, Francesco Cavaliere and 3 more

Abstract read
In one paragraph

Article in 3D printing and additive manufacturing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Elisa LegnaniCIMAINA and Department of Physics, University of Milano, Milan, Italy.
Pasqualina GalloFondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Milan, Italy.
Federico PezzottaCIMAINA and Department of Physics, University of Milano, Milan, Italy.ORCID https://orcid.org/0000-0002-0140-1346
Francesco PadelliFondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Milan, Italy.
Giuseppe FaragòFondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Milan, Italy.
Andrea GioppoFondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Milan, Italy.
Lorenzo GentiliCIMAINA and Department of Physics, University of Milano, Milan, Italy.
Elena De MartinFondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Milan, Italy.
Maria Luisa FumagalliFondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Milan, Italy.
Francesco CavaliereCIMAINA and Department of Physics, University of Milano, Milan, Italy.
Maria Grazia BruzzoneFondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Milan, Italy.
Paolo MilaniCIMAINA and Department of Physics, University of Milano, Milan, Italy.
Tommaso SantanielloCIMAINA and Department of Physics, University of Milano, Milan, Italy.ORCID https://orcid.org/0000-0003-1029-0307

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, an efficient methodology for manufacturing a realistic three-dimensional (3D) cerebrovascular phantom resembling a brain arteriovenous malformation (AVM) for applications in stereotactic radiosurgery is presented. The AVM vascular structure was 3D reconstructed from brain computed tomography (CT) data acquired from a patient. For the phantom fabrication, stereolithography was used to produce the AVM model and combined with silicone casting to mimic the brain parenchyma surrounding the vascular structure. This model was made with tissues-equivalent materials for radiology. The hollow vascular system of the phantom was filled with a contrast agent usually employed on patients for CT scans. The radiological response of the phantom was tested and compared with the one of the clinical case. The constructed model demonstrated to be a very accurate physical representation of the AVM and its vasculature and good morphological consistency was observed between the model and the patient-specific source anatomy. These results suggest that the proposed method has potential to be used to fabricate patient-specific phantoms for neurovascular radiosurgery applications and medical research.

Indexed as

additive manufacturinganthropomorphic phantomsstereolithographysurgical applicationstissue-equivalent materials

Identifiers

PMID36654837
PMCPMC9828616

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.