Evidence map›Paper›PMID 36654788›Full record

ArticleCurrent medical mycology2022

Synthesis and antifungal activity of novel griseofulvin nanoparticles with zinc oxide against dermatophytic fungi:

Ali Abdul Hussein S Al-Janabi, Abas Matrood Bashi

Open access · diamondAbstract read
In one paragraph

Article in Current medical mycology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ali Abdul Hussein S Al-JanabiDepartment of Microbiology, College of Medicine, University of Karbala, Iraq.
Abas Matrood BashiDepartment of Clinical Laboratories, College of AMS, University of Karbala, Iraq.
University of Karbala · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose: Dermatophytoses is an important type of skin disease caused by dermatophytes. The long-term treatment of this disease with standard antifungal agents may be improved through the application of nanotechnology. This study aimed to prepare nanoparticles of griseofulvin with zinc oxide and assess its antifungal action. Materials and Methods: Nanoparticles of griseofulvin with zinc oxide (GF-ZnO NPs) were prepared. Physical characteristics of new preparation and antidermatophytic action against two species of dermatophytes ( Results: Physical examination indicated that GF-ZnO NPs had typical nanoparticle characteristics. A new formulation showed effective inhibitory action against two fungal species with higher efficiency than that of griseofulvin. Conclusion: GF-ZnO NPs revealed an effective action against dermatophytes compared to griseofulvin alone. Nanoparticles containing griseofulvin may be used in the development of a novel drug for the treatment of dermatophytosis.

Indexed as

DermatophytesGriseofulvinNanoparticlesZnO

Identifiers

PMID36654788
PMCPMC9825792
OpenAlexW4312765220

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.