Evidence map›Paper›PMID 36654555›Full record

ArticleCureus2022

Essential Thrombocytosis in Patients <40 Years Old With Acute Coronary Syndromes: A Not So Uncommon Underlying Diagnosis Often Overlooked.

Lisa Kok, Laura F Taverne, Eva C Verbeek, Machiel van de Wetering, Albertus J Voogel, Liane Oosterom, Jean-Paul R Herrman, Remko S Kuipers

Abstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Essential thrombocytosis: diagnosis, differential diagnosis, complications and treatment considerations of relevance for a cardiologist.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lisa KokCardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, NLD.
Laura F TaverneCardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, NLD.
Eva C VerbeekCardiothoracic Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, NLD.
Machiel van de WeteringCardiology, BovenIJ Ziekenhuis, Amsterdam, NLD.
Albertus J VoogelCardiology, Spaarne Ziekenhuis, Haarlem, NLD.
Liane OosteromCardiology, Dijklander Ziekenhuis Purmerend, Purmerend, NLD.
Jean-Paul R HerrmanCardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, NLD.
Remko S KuipersCardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, NLD.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients under <40 years, traditional cardiovascular (CV)-risk factors are a less likely cause of acute coronary syndromes (ACS) compared to older counterparts.

aimsTo estimate the prevalence of essential thrombocytosis (ET), a hematological disorder and less-prevalent risk factor, in young patients presenting with ACS.

methodsWe constructed a retrospective database of all patients <40 years (n=271) that had consecutively undergone coronary angiography (CAG) after their

resultsIn our database, we identified 15 subjects with thrombocytosis. One was previously known as ET. Of the remaining 14 patients, five were considered reactive/secondary thrombocytosis, and four were lost to follow-up, four were eventually diagnosed with ET, one remains uncertain. The diagnosis was newly established before the initiation of this study in two patients (average delay: six years). Two patients were identified as a result of this study.  Conclusion: With a prevalence of at least 2.1%, ET appears not uncommon in patients <40 years with ACS. Moreover, screening patients with ACS

Indexed as

acute coronary syndromeessential thrombocytosismyeloproliferative neoplasmtraditional risk factorsyoung adults

Identifiers

PMID36654555
PMCPMC9842111

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