Evidence map›Paper›PMID 36653768›Full record

ArticleBMC pediatrics2023

Implementation of an integrated care strategy for child contacts of tuberculosis patients: a quasi-experimental study protocol.

Dione Benjumea-Bedoya, Esteban Villegas Arbeláez, Daniela Martínez-Peñaloza, Claudia Patricia Beltrán-Arroyave, Andrea Victoria Restrepo Gouzy, Diana Marín, Lina Marcela Cadavid Álvarez, Beatriz Molinares, Fernando Nicolás Montes Zuluaga, Henry Pulido Duarte and 12 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04331262 (Tuberculosis en Niños), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04331262 completednot on this map

Tuberculosis en Niños: Implementación de Una Estrategia de Cuidado Integral Para Los Niños Contacto de Pacientes Con Tuberculosis Pulmonar Bacilífera

TypeobservationalSponsorCorporacion para Investigaciones BiologicasRan2021 to 2023Enrolled163ConditionsLatent Tuberculosis
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Guideline
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 5 institutions in 1 country.

Dione Benjumea-BedoyaUnidad de Bacteriología y Micobacterias, Corporación para Investigaciones Biológicas, Universidad Pontificia Bolivariana, Medellín, Colombia. dionebenjumea@gmail.com.ORCID 0000-0002-4004-2219
Esteban Villegas ArbeláezUnidad de Bacteriología y Micobacterias, Corporación para Investigaciones Biológicas, Universidad Pontificia Bolivariana, Medellín, Colombia.
Daniela Martínez-PeñalozaUnidad de Bacteriología y Micobacterias, Corporación para Investigaciones Biológicas, Universidad Pontificia Bolivariana, Medellín, Colombia.
Claudia Patricia Beltrán-ArroyaveGrupo Pediaciencias, Medicine School, Universidad de Antioquia, Medellín, Colombia.
Andrea Victoria Restrepo GouzyHospital Pablo Tobón Uribe, Medellín, Colombia.
Diana MarínGrupo de Investigación en Salud Pública, School of Health Sciences, Universidad Pontificia Bolivariana, Medellín, Colombia.
Lina Marcela Cadavid ÁlvarezHospital Pablo Tobón Uribe, Medellín, Colombia.
Beatriz MolinaresHospital Pablo Tobón Uribe, Medellín, Colombia.
Fernando Nicolás Montes ZuluagaTuberculosis Program, Secretariat of Health of Medellín, Medellín, Colombia.
Henry Pulido DuarteTuberculosis Program, Secretariat of Health of Bello, Bello, Colombia.
Pedro Mauricio Suárez ParraTuberculosis Program, Secretariat of Health of Itagüí, Itagüí, Colombia.
Juan Carlos Alzate ÁngelGrupo de Epidemiología, Facultad Nacional de Salud Pública, Universidad de Antioquia, Medellín, Colombia.
Guillermo Vélez-ParraHospital General de Medellín, Professor Universidad CES, Medellín, Colombia.
Teresa RealpeUnidad de Bacteriología y Micobacterias, Corporación para Investigaciones Biológicas, Universidad Pontificia Bolivariana, Medellín, Colombia.
Marisol Vásquez VillaUnidad de Bacteriología y Micobacterias, Corporación para Investigaciones Biológicas, Universidad Pontificia Bolivariana, Medellín, Colombia.
Stefani Yamile Ríos BuitragoUnidad de Bacteriología y Micobacterias, Corporación para Investigaciones Biológicas, Universidad Pontificia Bolivariana, Medellín, Colombia.
Jenifer Puerta ZapataUnidad de Bacteriología y Micobacterias, Corporación para Investigaciones Biológicas, Universidad Pontificia Bolivariana, Medellín, Colombia.
Lisandra María Arango GarcíaUnidad de Bacteriología y Micobacterias, Corporación para Investigaciones Biológicas, Universidad Pontificia Bolivariana, Medellín, Colombia.
Yesenia Perea TorresUnidad de Bacteriología y Micobacterias, Corporación para Investigaciones Biológicas, Universidad Pontificia Bolivariana, Medellín, Colombia.
Natalia Pérez DoncelSchool of Health Sciences, Universidad Pontificia Bolivariana, Medellín, Colombia.
María Patricia Arbeláez MontoyaGrupo de Epidemiología, Facultad Nacional de Salud Pública, Universidad de Antioquia, Medellín, Colombia.
Jaime RobledoUnidad de Bacteriología y Micobacterias, Corporación para Investigaciones Biológicas, Universidad Pontificia Bolivariana, Medellín, Colombia.
Universidad Pontificia Bolivariana · COHospital Pablo Tobon Uribe · COUniversidad de Antioquia · COMunicipality of Medellín · COSecretaría de Salud de Bogotá · CO

Funding

Ministerio de Ciencia Tecnología e Innovación de Colombia 088-2021Ministerio de Ciencia Tecnología e Innovación de Colombia 902-2019
6 · The paper itself

Abstract

backgroundChildhood tuberculosis continues to be a major public health problem. Although the visibility of the epidemic in this population group has increased, further research is needed.

objectiveTo design, implement and evaluate an integrated care strategy for children under five years old who are household contacts of bacteriologically confirmed pulmonary tuberculosis patients in Medellín and the Metropolitan Area.

methodsA quasi-experimental study in which approximately 300 children who are household contacts of bacteriologically confirmed pulmonary tuberculosis patients from Medellín and the Metropolitan Area will be evaluated and recruited over one year. A subgroup of these children, estimated at 85, who require treatment for latent tuberculosis, will receive an integrated care strategy that includes: some modifications of the current standardized scheme in Colombia, with rifampicin treatment daily for four months, follow-up under the project scheme with nursing personnel, general practitioners, specialists, professionals from other disciplines such as social work, psychology, and nutritionist. Additionally, transportation and food assistance will be provided to encourage treatment compliance. This strategy will be compared with isoniazid treatment received by a cohort of children between 2015 and 2018 following the standardized scheme in the country. The study was approved by the CIB Research Ethics Committee and UPB. CLINICALTRIALS: gov identifier NCT04331262. DISCUSSION: This study is expected to contribute to the development of integrated care strategies for the treatment of latent tuberculosis in children. The results will have a direct impact on the management of childhood tuberculosis contributing to achieving the goals proposed by the World Health Organization's End TB Strategy.

trial registrationClinicalTrials.gov identifier NCT04331262 . Implementation of an Integrated Care Strategy for Children Contacts of Patients with Tuberculosis. Registered 2 April 2020.

Indexed as

Delivery of Health Care, IntegratedLatent TuberculosisTuberculosisTuberculosis, PulmonaryChildChild, PreschoolHumansIsoniazidIsoniazidChild, PreschoolComprehensive Health CareLatent TuberculosisPerson-Centered CareRifampin

Identifiers

PMID36653768
PMCPMC9850583
OpenAlexW4317372342

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.