Evidence map›Paper›PMID 36653744›Full record

ArticleACS infectious diseases2023

Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins from

Filippo Favretto, Eva Jiménez-Faraco, Carolina Conter, Paola Dominici, Juan A Hermoso, Alessandra Astegno

Open access · hybridAbstract read
In one paragraph

Article in ACS infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Insights into Peptidyl-ProlylPathogens (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Filippo FavrettoDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134Verona, Italy.
Eva Jiménez-FaracoDepartment of Crystallography and Structural Biology, Institute of Physical Chemistry Rocasolano (IQFR), CSIC, Serrano 119, 28006Madrid, Spain.ORCID 0000-0002-5548-3252
Carolina ConterDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134Verona, Italy.
Paola DominiciDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134Verona, Italy.
Juan A HermosoDepartment of Crystallography and Structural Biology, Institute of Physical Chemistry Rocasolano (IQFR), CSIC, Serrano 119, 28006Madrid, Spain.ORCID 0000-0002-1862-8950
Alessandra AstegnoDepartment of Biotechnology, University of Verona, Strada Le Grazie 15, 37134Verona, Italy.ORCID 0000-0002-7341-0970
University of Verona · ITInstituto de Química Física Blas Cabrera · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclosporin (CsA) has antiparasite activity against the human pathogen

Indexed as

CyclophilinsToxoplasmaBinding SitesCyclosporineProtein IsoformsCyclophilinsCyclosporineProtein Isoformschaperone-like activitycrystal structurecyclophilincyclosporinpeptidyl-prolyl isomerizationToxoplasma gondii

Identifiers

PMID36653744
PMCPMC9926490
OpenAlexW4317374018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.