Evidence map›Paper›PMID 36653362›Full record

ArticleNature communications2023

An integrated Mg battery-powered iontophoresis patch for efficient and controllable transdermal drug delivery.

Yan Zhou, Xiaoteng Jia, Daxin Pang, Shan Jiang, Meihua Zhu, Geyu Lu, Yaping Tian, Caiyun Wang, Danming Chao, Gordon Wallace

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Biointegrated Battery-Based Electroceuticals.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Galvanic-Cell-Based Self-Powered Bioelectronic Devices.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  15. Article
  16. Review
  17. Smart Hydrogels in Wearable Electronics for Wound Treatments.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  18. Smart closed-loop drug delivery systems.Nature reviews bioengineering · 2025
    Article
  19. Gel-Based Ionic Circuits.Chemical reviews · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan ZhouCollege of Chemistry, Jilin University, Changchun, 130012, China.
Xiaoteng JiaState Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, 130012, China. xtjia@jlu.edu.cn.ORCID 0000-0001-5630-8838
Daxin PangCollege of Animal Sciences, Jilin University, Changchun, 130062, China.
Shan JiangCollege of Chemistry, Jilin University, Changchun, 130012, China.
Meihua ZhuCollege of Chemistry, Jilin University, Changchun, 130012, China.
Geyu LuState Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, 130012, China.
Yaping TianDepartment of Dermatology and Venerology, The First Hospital of Jilin University, Changchun, 130021, China. typ@jlu.edu.cn.ORCID 0000-0001-9800-5026
Caiyun WangARC Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, AIIM Facility, University of Wollongong, North Wollongong, NSW, Australia. caiyun@uow.edu.au.ORCID 0000-0001-9539-2155
Danming ChaoCollege of Chemistry, Jilin University, Changchun, 130012, China. chaodanming@jlu.edu.cn.ORCID 0000-0003-1324-6731
Gordon WallaceARC Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, AIIM Facility, University of Wollongong, North Wollongong, NSW, Australia.ORCID 0000-0002-0381-7273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wearable transdermal iontophoresis eliminating the need for external power sources offers advantages for patient-comfort when deploying epidermal diseases treatments. However, current self-powered iontophoresis based on energy harvesters is limited to support efficient therapeutic administration over the long-term operation, owing to the low and inconsistent energy supply. Here we propose a simplified wearable iontophoresis patch with a built-in Mg battery for efficient and controllable transdermal delivery. This system decreases the system complexity and form factors by using viologen-based hydrogels as an integrated drug reservoir and cathode material, eliminating the conventional interface impedance between the electrode and drug reservoir. The redox-active polyelectrolyte hydrogel offers a high energy density of 3.57 mWh cm

Indexed as

IontophoresisSkinAdministration, CutaneousAnimalsDrug Delivery SystemsHydrogelsMiceSkin AbsorptionHydrogels

Identifiers

PMID36653362
PMCPMC9849227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.