ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023
Brain State-Dependent Modulation of Thalamic Visual Processing by Cortico-Thalamic Feedback.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Temporal kinetics of brain state effects on visual perception.Scientific reports · 2026Article
- Behavioural states control binocular vision through input-specific mechanisms.Nature communications · 2026Article
- An adaptive and flexible role for primary sensory cortex.Nature neuroscience · 2026Review
- Article
- Effects of corticothalamic feedback depend on visual responsiveness and stimulus type.iScience · 2025Article
- Corticothalamic modulation of somatosensory thalamic tactile processing.The Journal of physiology · 2025Article
- Environmental context influences visual processing in thalamus.Current biology : CB · 2025Article
- Higher-order thalamic input to cortex selectively conveys state information.Cell reports · 2025Article
- Altered brain structural covariance networks of the thalamic subfields in right chronic capsular stroke.Frontiers in neuroscience · 2025Article
- Article
- Motor Control of Distinct Layer 6 Corticothalamic Feedback Circuits.bioRxiv : the preprint server for biology · 2024Article
- Dynamic corticothalamic modulation of the somatosensory thalamocortical circuit during wakefulness.Nature communications · 2024Article
- Sensory cortical ensembles exhibit differential coupling to ripples in distinct hippocampal subregions.Current biology : CB · 2023Article
- Transthalamic input to higher-order cortex selectively conveys state information.bioRxiv : the preprint server for biology · 2023Article
- Sensory cortical ensembles exhibit differential coupling to ripples in distinct hippocampal subregions.bioRxiv : the preprint server for biology · 2023Article
- Article
- Flicker light stimulation induces thalamocortical hyperconnectivity with LGN and higher-order thalamic nuclei.Imaging neuroscience (Cambridge, Mass.) · 2023Article
- Robust effects of corticothalamic feedback and behavioral state on movie responses in mouse dLGN.eLife · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
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Abstract
The behavioral state of a mammal impacts how the brain responds to visual stimuli as early as in the dorsolateral geniculate nucleus of the thalamus (dLGN), the primary relay of visual information to the cortex. A clear example of this is the markedly stronger response of dLGN neurons to higher temporal frequencies of the visual stimulus in alert as compared with quiescent animals. The dLGN receives strong feedback from the visual cortex, yet whether this feedback contributes to these state-dependent responses to visual stimuli is poorly understood. Here, we show that in male and female mice, silencing cortico-thalamic feedback profoundly reduces state-dependent differences in the response of dLGN neurons to visual stimuli. This holds true for dLGN responses to both temporal and spatial features of the visual stimulus. These results reveal that the state-dependent shift of the response to visual stimuli in an early stage of visual processing depends on cortico-thalamic feedback.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.