ArticleArchives of disease in childhood. Fetal and neonatal edition2023
Survey of transfusion practices in preterm infants in Europe.
Article in Archives of disease in childhood. Fetal and neonatal edition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The trial behind it
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Plasma transfusion in neonatal sepsis.World journal of pediatrics : WJP · 2026Article
- Pre-transfusion platelet counts and bleeding in very low birth weight infants.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Pre-Transfusion Platelet Counts and Bleeding in Very Low Birth Weight Infants.Research square · 2026Article
- Effect of fresh-frozen plasma transfusion on intraventricular hemorrhage risk in preterm infants with prolonged APTT: a target trial emulation with causal forest analysis.Frontiers in neuroscience · 2026Article
- Identifying barriers to complying with new restrictive NICU transfusion guidelines.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Observational
- Plasma transfusions in neonatal intensive care units: a prospective observational study.Archives of disease in childhood. Fetal and neonatal edition · 2025Observational
- Current red blood cell and platelet transfusion practices in Canadian neonatal intensive care units.Transfusion · 2025Article
- If things were simple, word would have gotten around. Can complexity science help us improve pediatric research?Pediatric research · 2025Review
- Severe anemia in preterm infants associated with increased bacterial virulence potential and metabolic disequilibrium.Pediatric research · 2025Article
- Adverse outcomes after red blood cell transfusion in very low birth weight infants in a resource-restricted hospital.Transfusion · 2025Article
- Early plasma ferritin concentrations are not associated with time to red cell transfusions in extremely and very preterm neonates: a prospective single-site observational study.BMJ paediatrics open · 2025Observational
- The number of blood transfusions received and the incidence and severity of chronic lung disease among NICU patients born >31 weeks gestation.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Fetal Hemoglobin as a Predictive Biomarker for Retinopathy of Prematurity: A Prospective Multicenter Cohort Study in Portugal.Biomedicines · 2025Article
- Coagulation assay results at birth in preterm infants: A cohort study highlighting the relevance of local reference values for interpretation.Vox sanguinis · 2025Article
- Transfusion Practices in 12 Neonatal Networks: Are We Closer to Adopting a Restrictive Transfusion Approach?Neonatology · 2025Article
- Platelet transfusion in neonatal intensive care units of 22 European countries: a prospective observational study.The Lancet regional health. Europe · 2024Article
- Red Blood Cell Transfusion for Incidence of Retinopathy of Prematurity: Prospective Multicenter Cohort Study.JMIR pediatrics and parenting · 2024Article
- Red Blood Cell Transfusion in European Neonatal Intensive Care Units, 2022 to 2023.JAMA network open · 2024Observational
- Why might cord blood be a better source of platelets for transfusion to neonates?Blood transfusion = Trasfusione del sangue · 2024Review
Corrections and comments
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Authors and funding
26 authors at 20 institutions in 18 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreterm infants commonly receive red blood cell (RBC), platelet and fresh frozen plasma (FFP) transfusions. The aim of this Neonatal Transfusion Network survey was to describe current transfusion practices in Europe and to compare our findings to three recent randomised controlled trials to understand how clinical practice relates to the trial data.
methodsFrom October to December 2020, we performed an online survey among 597 neonatal intensive care units (NICUs) caring for infants with a gestational age (GA) of <32 weeks in 18 European countries.
resultsResponses from 343 NICUs (response rate: 57%) are presented and showed substantial variation in clinical practice. For RBC transfusions, 70% of NICUs transfused at thresholds above the restrictive thresholds tested in the recent trials and 22% below the restrictive thresholds. For platelet transfusions, 57% of NICUs transfused at platelet count thresholds above 25×10
conclusionsTransfusion thresholds and aspects of administration vary widely across European NICUs. In general, transfusion thresholds used tend to be more liberal compared with data from recent trials supporting the use of more restrictive thresholds. Further research is needed to identify the barriers and enablers to incorporation of recent trial findings into neonatal transfusion practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.