Evidence map›Paper›PMID 36653057›Full record

Trial reportBMJ open2023

Examining the benefit of graduated compression stockings in the prevention of hospital-associated venous thromboembolism in low-risk surgical patients: a multicentre cluster randomised controlled trial (PETS trial).

Matthew Machin, Sarrah Peerbux, Sarah Whittley, Beverley J Hunt, Tamara Everington, Manjit Gohel, John Norrie, David Epstein, David J Warwick, Christopher Baker and 7 more

Open access · goldAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Elastic stockings for venous thromboembolism prevention, time to go.Research and practice in thrombosis and haemostasis · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 2 countries.

Matthew MachinSection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, London, UK.
Sarrah PeerbuxSection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, London, UK.ORCID 0000-0001-5560-0749
Sarah WhittleySection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, London, UK.ORCID 0000-0002-8757-2487
Beverley J HuntThrombosis & Haemophilia Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Tamara EveringtonHampshire Hospitals NHS Foundation Trust, Winchester, Hampshire, UK.
Manjit GohelDepartment of Vascular Surgery, Addenbrooke's Hospital, Cambridge, UK.
John NorrieUsher Institute of Population Health Sciences and Informatics, Edinburgh Clinical Trials Unit, University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-9823-9252
David EpsteinFaculty of Economic and Business Sciences, University of Granada, Granada, Spain.
David J WarwickUniversity Hospital Southampton NHS Foundation Trust, Southampton, UK.
Christopher BakerImperial Vascular Unit, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
Zaed HamadyGeneral Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Sasha SmithSection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, London, UK.
Layla BoltonImperial Vascular Unit, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
Annya Stephens-BoalSection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, London, UK.
Beverley GraySection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, London, UK.
Joseph ShalhoubSection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, London, UK.
Alun Huw DaviesSection of Vascular Surgery, Department of Surgery and Cancer, Charing Cross Hospital, Imperial College London, London, UK a.h.davies@imperial.ac.uk.
Charing Cross Hospital · GBImperial College Healthcare NHS Trust · GBUniversity Hospital Southampton NHS Foundation Trust · GBAddenbrooke's Hospital · GBGuy's and St Thomas' NHS Foundation Trust · GBHampshire Hospitals NHS Foundation Trust · GBUniversidad de Granada · ESUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHospital-acquired thrombosis (HAT) is defined as any venous thromboembolism (VTE)-related event during a hospital admission or occurring up to 90 days post discharge, and is associated with significant morbidity, mortality and healthcare-associated costs. Although surgery is an established risk factor for VTE, operations with a short hospital stay (<48 hours) and that permit early ambulation are associated with a low risk of VTE. Many patients undergoing short-stay surgical procedures and who are at low risk of VTE are treated with graduated compression stockings (GCS). However, evidence for the use of GCS in VTE prevention for this cohort is poor. METHODS AND ANALYSIS: A multicentre, cluster randomised controlled trial which aims to determine whether GCS are superior in comparison to no GCS in the prevention of VTE for surgical patients undergoing short-stay procedures assessed to be at low risk of VTE. A total of 50 sites (21 472 participants) will be randomised to either intervention (GCS) or control (no GCS). Adult participants (18-59 years) who undergo short-stay surgical procedures and are assessed as low risk of VTE will be included in the study. Participants will provide consent to be contacted for follow-up at 7-days and 90-days postsurgical procedure. The primary outcome is the rate of symptomatic VTE, that is, deep vein thrombosis or pulmonary embolism during admission or within 90 days. Secondary outcomes include healthcare costs and changes in quality of life. The main analysis will be according to the intention-to-treat principle and will compare the rates of VTE at 90 days, measured at an individual level, using hierarchical (multilevel) logistic regression. ETHICS AND DISSEMINATION: Ethical approval was granted by the Camden and Kings Cross Research Ethics Committee (22/LO/0390). Findings will be published in a peer-reviewed journal and presented at national and international conferences. TRIAL REGISTRATION NUMBER: ISRCTN13908683.

Indexed as

Venous ThromboembolismAdultAftercareAnticoagulantsHospitalsHumansPatient DischargeQuality of LifeStockings, CompressionAnticoagulantssurgerythromboembolismvascular medicine

Identifiers

PMID36653057
PMCPMC9853211
OpenAlexW4317477982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.