Evidence map›Paper›PMID 36652520›Full record

ArticleScience advances2023

Using digital traces to build prospective and real-time county-level early warning systems to anticipate COVID-19 outbreaks in the United States.

Lucas M Stolerman, Leonardo Clemente, Canelle Poirier, Kris V Parag, Atreyee Majumder, Serge Masyn, Bernd Resch, Mauricio Santillana

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
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  19. Emergence of the reproduction matrix in epidemic forecasting.Journal of the Royal Society, Interface · 2024
    Article
  20. Innovations in public health surveillance: An overview of novel use of data and analytic methods.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Lucas M StolermanComputational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0001-6313-0126
Leonardo ClementeComputational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0003-1622-0537
Canelle PoirierComputational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-6972-2621
Kris V ParagNIHR Health Protection Research Unit, Behavioural Science and Evaluation, University of Bristol, Bristol, UK.ORCID 0000-0002-7806-3605
Atreyee MajumderGlobal Public Health, Janssen R&D, Beerse, Belgium.ORCID 0000-0002-8185-5785
Serge MasynGlobal Public Health, Janssen R&D, Beerse, Belgium.ORCID 0000-0002-4296-1809
Bernd ReschDepartment of Geoinformatics - Z-GIS, University of Salzburg, Salzburg, Austria.ORCID 0000-0002-2233-6926
Mauricio SantillanaDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-4206-418X
Boston Children's Hospital · USJanssen (Belgium) · BEHarvard University · USNortheastern University · USOklahoma State University · USUniversity of Bristol · GB

Funding

Development of an Open-Source and Data-Driven Modeling Platform to Monitor and Forecast Disease ActivityR01GM130668 · NIGMS · NORTHEASTERN UNIVERSITY · PI SANTILLANA, MAURICIO · 2018 to 2022
$1.9M
Medical Research Council MR/R015600/1NIGMS NIH HHS R01 GM130668
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) continues to affect the world, and the design of strategies to curb disease outbreaks requires close monitoring of their trajectories. We present machine learning methods that leverage internet-based digital traces to anticipate sharp increases in COVID-19 activity in U.S. counties. In a complementary direction to the efforts led by the Centers for Disease Control and Prevention (CDC), our models are designed to detect the time when an uptrend in COVID-19 activity will occur. Motivated by the need for finer spatial resolution epidemiological insights, we build upon previous efforts conceived at the state level. Our methods-tested in an out-of-sample manner, as events were unfolding, in 97 counties representative of multiple population sizes across the United States-frequently anticipated increases in COVID-19 activity 1 to 6 weeks before local outbreaks, defined when the effective reproduction number

Identifiers

PMID36652520
PMCPMC9848273
OpenAlexW4317254666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.