ArticleAmerican journal of physiology. Endocrinology and metabolism2023
The role of preproglucagon peptides in regulating β-cell morphology and responses to streptozotocin-induced diabetes.
Deanna M Arble, Chelsea R Hutch, Hannah Hafner, Daria Stelmak, Kyle Leix, Joyce Sorrell, Joshua W Pressler, Brigid Gregg, Darleen A Sandoval
Open access · greenAbstract read
In one paragraphArticle in American journal of physiology. Endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors at 4 institutions in 1 country.
Deanna M ArbleDepartment of Biological Sciences, Marquette University, Milwaukee, Wisconsin, United States.
Chelsea R HutchDepartment of Surgery, University of Michigan, Ann Arbor, Michigan, United States.
Hannah HafnerDepartment of Pediatrics, Division of Diabetes, Endocrinology and Metabolism, University of Michigan Medicine, Ann Arbor, Michigan, United States.
Daria StelmakDepartment of Surgery, University of Michigan, Ann Arbor, Michigan, United States.
Kyle LeixDepartment of Surgery, University of Michigan, Ann Arbor, Michigan, United States.
Joyce SorrellDepartment of Internal Medicine, University of Cincinnati, Cincinnati, Ohio, United States.
Joshua W PresslerDepartment of Internal Medicine, University of Cincinnati, Cincinnati, Ohio, United States.
Brigid GreggDepartment of Pediatrics, Division of Diabetes, Endocrinology and Metabolism, University of Michigan Medicine, Ann Arbor, Michigan, United States.ORCID 0000-0002-1192-2997 Darleen A SandovalDepartment of Pediatrics, Section of Nutrition and Division of Endocrinology, Metabolism and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0003-3669-3278 University of Michigan · USUniversity of Colorado Anschutz Medical Campus · USMarquette University · USMichigan United · US
Funding
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WILLIAM H HERMAN · 2013 to 2026
$24.3MUniversity of Colorado Anschutz Medical Campus DRCP30DK116073 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI LORI SUSSEL · 2020 to 2026
$10.8MMechanisms of Post-Bariatric HypoglycemiaR01DK121995 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PATTI, MARY E, SANDOVAL, DARLEEN A. · 2019 to 2022
$2.8MA novel paracrine role for GLP-1 in the isletR01DK107282 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANDOVAL, DARLEEN A. · 2017 to 2020
$1.6MProgramming of beta-cells and Glucose Homeostasis by Maternal Metformin ExposureK08DK102526 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GREGG, BRIGID ELLEN · 2015 to 2021
$797kNIDDK NIH HHS K08 DK102526NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK116073NIDDK NIH HHS R01 DK107282NIDDK NIH HHS R01 DK121995
6 · The paper itselfAbstract
Insulin secretion from β-cells is tightly regulated by local signaling from preproglucagon (
Indexed as
Diabetes Mellitus, ExperimentalGlucagon-Secreting CellsHyperglycemiaAnimalsBlood GlucoseGlucoseInsulinMiceMice, KnockoutProglucagonStreptozocinBlood GlucoseGlucoseInsulinProglucagonStreptozocindiabetesGLP-1glucagoninsulinpreproglucagon
Identifiers
PMID36652401
PMCPMC9970646
OpenAlexW4317360505
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