ArticleGenome biology and evolution2023
Chromosome-Level Genome Assembly of Herpetospermum pedunculosum (Cucurbitaceae).
Article in Genome biology and evolution, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Genome-wide identification of NAC transcription factors in Herpetospermum pedunculosum and expression analysis under salt stress.Genes & genomics · 2026Article
- A RUBY-Assisted Hairy Root Transformation Platform for Metabolomic Profiling and Preliminary Functional Analysis ofPlants (Basel, Switzerland) · 2026Article
- Genome-wide identification and functional characterization of bHLH transcription factors in Herpetospermum pedunculosum under salt stress.BMC plant biology · 2026Article
- Establishment of efficient Trichosanthes mottle mosaic virus-derived gene silencing in cucurbit plants.Stress biology · 2025Article
- Genome-wide characterization of theFrontiers in plant science · 2025Article
- Integrative analysis of the metabolome and transcriptome provides insights into the mechanisms of lignan biosynthesis in Herpetospermum pedunculosum (Cucurbitaceae).BMC genomics · 2024Article
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Authors and funding
7 authors.
Funding
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Abstract
This study presents a chromosome-level reference genome assembly of a traditional Tibetan medicinal plant, Herpetospermum pedunculosum belonging to the Cucurbitaceae family. Following a combined PacBio high-fidelity sequencing and Hi-C analysis, a final H. pedunculosum genome assembly, 804.11 Mb in length was obtained, 90.45% of which was anchored into ten pseudochromosomes with a contig N50 of 24.39 Mb. In addition, 579.55 Mb repetitive sequences and 23,924 high-confidence protein-coding genes were annotated. Phylogenetic analysis revealed that H. pedunculosum was sister to a clade formed by cucumber, zucchini, and wax gourd. Further whole-genome duplication analysis revealed no recent polyploidization event in the H. pedunculosum genome. The high-quality H. pedunculosum genome presented here will be highly useful in investigating the molecular mechanisms underlying the biosynthesis of its active compounds and adaptation strategies to the extreme environment. It will also provide great insights into comparative genomic studies of Cucurbitaceae and flowering plants.
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