Evidence map›Paper›PMID 36652383›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Venous Thromboembolism in Japanese Patients with Gynecologic Cancer.

Takahito Suzuki, Shota Tsurimoto, Takayasu Tada, Ryo Yamamura, Hiromasa Katoh, Yoshihiro Noji, Masato Yamaguchi, Susumu Fujino

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Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Takahito SuzukiDepartment of Cardiology, 13607Fukui Prefectural Hospital, Fukui, Japan.ORCID 0000-0002-8752-0695
Shota TsurimotoDepartment of Cardiology, 13607Fukui Prefectural Hospital, Fukui, Japan.
Takayasu TadaDepartment of Cardiology, 13607Fukui Prefectural Hospital, Fukui, Japan.
Ryo YamamuraDepartment of Cardiology, 13607Fukui Prefectural Hospital, Fukui, Japan.
Hiromasa KatohDepartment of Cardiology, 13607Fukui Prefectural Hospital, Fukui, Japan.
Yoshihiro NojiDepartment of Cardiology, 13607Fukui Prefectural Hospital, Fukui, Japan.
Masato YamaguchiDepartment of Cardiology, 13607Fukui Prefectural Hospital, Fukui, Japan.
Susumu FujinoDepartment of Cardiology, 13607Fukui Prefectural Hospital, Fukui, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGynecologic cancer, including cervical, endometrial, and ovarian cancer, comprises the fifth leading type of cancer and is an important malignant disease in women. Previous studies in Western countries have reported respective prevalence rates for venous thromboembolism (VTE) of 3.3%-18.7%, 0.8%-8.1%, and 7.2%-20.9%. In this study, we aimed to identify the characteristics associated with VTE in Japanese patients.

methodsWe carried out a retrospective cohort study to compare the clinicopathological characteristics of patients with each gynecologic cancer with and without concomitant VTE. Patients: Patients with cervical, endometrial, or ovarian cancer treated at Fukui Prefectural Hospital, Japan, from April 2010 to March 2020.

resultsAmong 699 patients with gynecologic cancer, 50 developed VTE within 5 years after their cancer diagnosis, including 16/357 patients with cervical cancer (5.6%), 12/185 with endometrial cancer (6.8%), and 22/157 with ovarian cancer (14.6%). The 1-year mortality rate after symptomatic VTE onset was 47.8%. The VTE group included significantly more older patients and more patients with advanced cancer or poor performance status compared with the non-VTE group. There was no significant difference in the rate of surgical treatment. Symptomatic, but not asymptomatic VTE, was associated with shorter survival.

conclusionSeveral baseline characteristics differed between patients with and without VTE. The incidences of VTE and some risk factors were similar in Japanese patients with gynecologic cancers compared with patients in other countries. Patients with VTE had some factors that worsened their prognosis, with patients with gynecologic cancer and symptomatic VTE having an especially poor prognosis.

Indexed as

Endometrial NeoplasmsOvarian NeoplasmsVenous ThromboembolismFemaleHumansIncidenceJapanRetrospective StudiesRisk Factorscervical cancerendometrial cancergynecologic cancerovarian cancervenous thromboembolism

Identifiers

PMID36652383
PMCPMC9893094

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