Evidence map›Paper›PMID 36652337›Full record

ArticleMolecular biology of the cell2023

KLHL12 can form large COPII structures in the absence of CUL3 neddylation.

Tamara Moretti, Kyungho Kim, Astha Tuladhar, Jinoh Kim

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular biology of the cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Tamara MorettiDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011.
Kyungho KimTargeted Therapy Branch, National Cancer Center, Goyang, Gyeonggi 10408, Republic of Korea.
Astha TuladharDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011.
Jinoh KimDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011.ORCID 0000-0003-2841-147X
Iowa State University · USNational Cancer Center · KR

Funding

Pathogenesis of diseases caused by aberrant COPII megavesicle assemblyR01GM110373 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KIM, JINOH · 2015 to 2019
$1.8M
Dysregulation of the unfolded protein response of the ER in nemaline myopathyR21AR075939 · NIAMS · IOWA STATE UNIVERSITY · PI KIM, JINOH · 2020 to 2021
$351k
NIAMS NIH HHS R21 AR075939NIGMS NIH HHS R01 GM110373
6 · The paper itself

Abstract

CUL3-RING ubiquitin ligases (CRL3s) are involved in various cellular processes through different Bric-a-brac, Tramtrack, and Broad-complex (BTB)-domain proteins. KLHL12, a BTB-domain protein, is suggested to play an essential role in the export of large cargo molecules such as procollagen from the endoplasmic reticulum (ER). CRL3

Indexed as

CollagenProcollagenAdaptor Proteins, Signal TransducingCOP-Coated VesiclesCullin ProteinsProtein BindingUbiquitinAdaptor Proteins, Signal TransducingCollagenCullin ProteinsProcollagenUbiquitin

Identifiers

PMID36652337
PMCPMC10011723
OpenAlexW4317241308

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.