ArticlePain and therapy2023
Stellate Ganglion Block Improves Postoperative Sleep Quality and Analgesia in Patients with Breast Cancer: A Randomized Controlled Trial.
Article in Pain and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sleep During Recovery: Does Preoperative Regional Block Affect Postoperative Sleep Quality in Mastectomy Patients? A Prospective Evaluation Using Two Validated Sleep Quality Scales
The Role of Regional Analgesia in Sleep Quality: Evaluation of Additional Regional Block in Total Abdominal Hysterectomy Patients
Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Effects of stellate ganglion block on postoperative sleep disturbance: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2026Pooled it
- Efficacy and safety of stellate ganglion block for postoperative pain management: a systematic review and meta-analysis of randomized controlled trials.BMC anesthesiology · 2026Pooled it
- A novel application of stellate ganglion block to improve sleep: a systematic review and meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Efficacy of ultrasound-guided stellate ganglion block in relieving acute postoperative pain: a systematic review and meta-analysis.The Journal of international medical research · 2024Pooled it
- Sympathetic nerve blocks for posttraumatic stress disorder: an evidentiary review for future clinical trials.Frontiers in psychiatry · 2023Pooled it
- Effect of high-frequency stellate ganglion block on sleep and affective symptoms in insomnia disorder: a prospective pilot study.BMC neurology · 2026Trial
- Dexmedetomidine Plus Stellate Ganglion Block Improves Postoperative Sleep Quality in Elderly Hip Arthroplasty Patients: A Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
- Perioperative stellate ganglion block improves early postoperative sleep after gynecological laparoscopic surgery: a randomized controlled trial.Frontiers in neuroscience · 2026Trial
- Preoperative Stellate Ganglion Block for Postoperative Sore Throat in Patients Undergoing Double-Lumen Endotracheal Intubation: A Randomized Clinical Trial.Drug design, development and therapy · 2026Trial
- Effect of Stellate Ganglion Block on Preventing Atrial Fibrillation After Esophagectomy: A Double-Blind Randomized Controlled Trial.Drug design, development and therapy · 2025Trial
- Preoperative Ultrasound-Guided Stellate Ganglion Block for Prevention of Postoperative Sore Throat After Thoracic Surgery: Study Protocol for a Randomized Controlled Trial.Journal of pain research · 2026Article
- Pharmacologic management of postoperative sleep disturbance in breast cancer.Frontiers in pharmacology · 2026Review
- Advances in the clinical application of stellate ganglion block for non-pain indications.Frontiers in medicine · 2026Review
- Effect of Stellate Ganglion Block on Postoperative Pain in Patients with Obstructive Sleep Apnea Syndrome: A Randomized Controlled Trial.Journal of pain research · 2026Article
- Effects of Preoperative Stellate Ganglion Block on Postoperative Sore Throat and Hoarseness in Patients Undergoing Double-Lumen Endobronchial Intubation: Protocol for a Prospective Randomized Controlled Trial.Journal of pain research · 2026Article
- Effect of Stellate Ganglion Block in Relieving Postoperative Pain After Surgery: A Systematic Review and Meta-Analysis.Journal of pain research · 2026Review
- Pupillary ultrasonography vs Horner's syndrome to evaluate efficacy of stellate ganglion block in patients.IBRO neuroscience reports · 2025Article
- Anatomy, Imaging, and Clinical Significance of the Cervicothoracic (Stellate) Ganglion.Diagnostics (Basel, Switzerland) · 2025Review
- Effect of linearly polarized light irradiation near stellate ganglion on postoperative sleep disorders in patients undergoing modified radical mastectomy of breast cancer.Perioperative medicine (London, England) · 2025Article
- The effect of ultrasound-guided single right stellate ganglion block on postoperative first night sleep in maxillofacial surgery patients: a single center randomized controlled study.Annals of medicine and surgery (2012) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
introductionPostoperative impaired sleep quality and pain are associated with adverse outcomes. Stellate ganglion block (SGB) has shown promising results in enhancing sleep quality and alleviating neuropathic pain. This study aimed to investigate the effects of ultrasound-guided SGB on postoperative sleep quality and pain in patients undergoing breast cancer surgery.
methodsThis study is a parallel-group randomized controlled clinical trial with two groups: SGB and control. Fifty female patients undergoing breast cancer surgery were randomized in a 1:1 ratio to receive preoperative ultrasound-guided single-injection SGB (SGB group) or just an ultrasound scan (control group). All participants were blinded to the group assignment. The primary outcome was postoperative sleep quality, assessed by the St. Mary's Hospital Sleep Questionnaire and actigraphy 2 days postoperatively. The secondary outcome was postoperative pain, measured by the visual analog scale.
resultsA total of 48 patients completed the study, with 23 patients in the control group and 25 in the SGB group. The postoperative St. Mary's Hospital Sleep Questionnaire scores were significantly higher in the SGB group than in the control group on 1 day postoperative (30.88 ± 2.44 versus 27.35 ± 4.12 points, P = 0.001). The SGB also increased the total sleep time and sleep efficiency (main actigraphy indicators) during the first two postoperative nights. Compared with the control group, preoperative SGB reduced postoperative pain and the incidence of breast cancer-related lymphedema (20% versus 52.2%, P = 0.02, odds ratio 0.229, 95% confidence interval 0.064-0.821). There were no adverse events related to SGB.
conclusionPreoperative ultrasound-guided SGB improves postoperative sleep quality and analgesia in patients undergoing breast cancer surgery. SGB may be a safe and practical treatment to enhance the postoperative quality of life in patients with breast cancer.
trial registrationThe study was registered in the Chinese Clinical Trial Registry (ChiCTR2100046620, principal investigator: Kai Zeng, date of registration: 23 May 2021).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.