Evidence map›Paper›PMID 36652027›Full record

ArticleAnnals of biomedical engineering2023

Effect of Active Muscles on Astronaut Kinematics and Injury Risk for Piloted Lunar Landing and Launch While Standing.

Mitesh Lalwala, Karan S Devane, Bharath Koya, Fang-Chi Hsu, Keegan M Yates, Nathaniel J Newby, Jeffrey T Somers, F Scott Gayzik, Joel D Stitzel, Ashley A Weaver

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Mitesh LalwalaDepartment of Biomedical Engineering, Wake Forest University School of Medicine, 575 N. Patterson Ave, Suite 530, Winston-Salem, NC, 27101, USA.
Karan S DevaneDepartment of Biomedical Engineering, Wake Forest University School of Medicine, 575 N. Patterson Ave, Suite 530, Winston-Salem, NC, 27101, USA.
Bharath KoyaDepartment of Biomedical Engineering, Wake Forest University School of Medicine, 575 N. Patterson Ave, Suite 530, Winston-Salem, NC, 27101, USA.
Fang-Chi HsuDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, 525 Vine Street, Winston-Salem, NC, 27101, USA.
Keegan M YatesKBR, 2400 NASA Parkway, Houston, TX, 77058, USA.
Nathaniel J NewbyKBR, 2400 NASA Parkway, Houston, TX, 77058, USA.
Jeffrey T SomersNASA Johnson Space Center, 2101 NASA Parkway, Houston, TX, 77058, USA.
F Scott GayzikDepartment of Biomedical Engineering, Wake Forest University School of Medicine, 575 N. Patterson Ave, Suite 530, Winston-Salem, NC, 27101, USA.
Joel D StitzelDepartment of Biomedical Engineering, Wake Forest University School of Medicine, 575 N. Patterson Ave, Suite 530, Winston-Salem, NC, 27101, USA.
Ashley A WeaverDepartment of Biomedical Engineering, Wake Forest University School of Medicine, 575 N. Patterson Ave, Suite 530, Winston-Salem, NC, 27101, USA. asweaver@wakehealth.edu.ORCID http://orcid.org/0000-0002-4383-0106
Virginia Tech - Wake Forest University School of Biomedical Engineering & Sciences · USKBR (United States) · USJohnson Space Center · USWake Forest University · US

Funding

NASA NNX16AP89G
6 · The paper itself

Abstract

While astronauts may pilot future lunar landers in a standing posture, the response of the human body under lunar launch and landing-related dynamic loading conditions is not well understood. It is important to consider the effects of active muscles under these loading conditions as muscles stabilize posture while standing. In the present study, astronaut response for a piloted lunar mission in a standing posture was simulated using an active human body model (HBM) with a closed-loop joint-angle based proportional integral derivative controller muscle activation strategy and compared with a passive HBM to understand the effects of active muscles on astronaut body kinematics and injury risk. While head, neck, and lumbar spine injury risk were relatively unaffected by active muscles, the lower extremity injury risk and the head and arm kinematics were significantly changed. Active muscle prevented knee-buckling and spinal slouching and lowered tibia injury risk in the active vs. passive model (revised tibia index: 0.02-0.40 vs. 0.01-0.58; acceptable tolerance: 0.43). Head displacement was higher in the active vs. passive model (11.6 vs. 9.0 cm forward, 6.3 vs. 7.0 cm backward, 7.9 vs. 7.3 cm downward, 3.7 vs. 2.4 cm lateral). Lower arm movement was seen with the active vs. passive model (23 vs. 35 cm backward, 12 vs. 20 cm downward). Overall simulations suggest that the passive model may overpredict injury risk in astronauts for spaceflight loading conditions, which can be improved using the model with active musculature.

Indexed as

AstronautsNeckBiomechanical PhenomenaHumansMuscle, SkeletalSpineArtemisBiomechanicsEffect sizeFinite element modelingGHBMCHuman body modelMoonMotion envelopeSpaceflightStanding posture

Identifiers

PMID36652027
OpenAlexW4317234392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.