Evidence map›Paper›PMID 36652009›Full record

SynthesisLangenbeck's archives of surgery2023

Is pain control for chronic neuropathic pain after inguinal hernia repair using endoscopic retroperitoneal neurectomy effective? A meta-analysis of 142 patients from 1995 to 2022.

Stephanie Taha-Mehlitz, Anas Taha, Alex Janzen, Baraa Saad, Dana Hendie, Vincent Ochs, Lukas Krähenbühl

Erratum issuedOpen access · hybridAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Stephanie Taha-Mehlitz *Clarunis, University Centre for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital, 4002, Basel, Switzerland.
Anas Taha *Department of Biomedical Engineering, Faculty of Medicine, University of Basel, 4123, Allschwil, Switzerland. anas.taha@unibas.ch.
Alex JanzenDepartment of Anesthesia, Greifswald University, 17489, Greifswald, Germany.
Baraa SaadFaculty of Medicine, St George's University of London, 2062, Nicosia, Cyprus.
Dana HendieDepartment of Surgery, College of Medicine, Sulaiman Al Rajhi University, Albukairyah, Saudi Arabia.
Vincent OchsRoche Innovation Centre Basel, Department of Pharma Research & Early Development, 4070, Basel, Switzerland.
Lukas KrähenbühlOncosurgery Zurich, 8802, Kilchberg/Zurich, Switzerland.
Roche (Switzerland) · CHSanatorium Kilchberg · CHSulaiman Al Rajhi Colleges · SAUniversität Greifswald · DEUniversity of Basel · CHUniversity of Nicosia · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNeuropathic pain is a complication after groin hernia surgery. Triple neurectomy of the iliohypogastric nerve, ilioinguinal nerve and genitofemoral nerve is an efficient treatment modality, with several surgical approaches. The minimally invasive endoscopic method to neurectomy was specifically investigated in this meta-analysis. Our aim is to determine the efficacy of this method in the treatment of chronic neuropathic pain posthernia repair surgery.

methodsA systematic review was conducted using four databases to search for the keywords ("endoscopic retroperitoneal neurectomy" and "laparoscopic retroperitoneal neurectomy"). The NCBI National Library of Medicine, Cochrane Library, MEDLINE Complete and BioMed Central were last searched on 26 May 2022. Randomised control trials and retrospective or prospective papers involving endoscopic retroperitoneal neurectomy operations after inguinal hernia repair were included. All other surgeries, procedures and study designs were excluded. The internal quality of included studies was assessed using the Newcastle-Ottawa Scale. The percentage of patients who had reduction in pain ("positive treatment outcome") was used to assess the procedure's effectiveness in each analysis.

resultsFive comparable endoscopic retroperitoneal neurectomy studies with a total of 142 patients were analysed. Both the Wald test (Q (6) = 1.79, = .775) and the probability ratio test (Q (6) = 4.24, = .374) provide similar findings (0.000, 0.0% [0.0%; 78%]). The meta-analysis' key finding is that the intervention was up to 78% effective (95% confidence interval, 71%; 84%).

conclusionEndoscopic retroperitoneal neurectomy can be an effective treatment option for postoperative neuropathic pain relief following surgical hernia repair. Although there is limited reported experience with this technique, it may provide a clinical benefit to the patient. We recommend further prospective data and long-term follow-up studies be conducted to confirm and expand on these outcomes.

Indexed as

Chronic PainHernia, InguinalLaparoscopyNeuralgiaDenervationHerniorrhaphyHumansPostoperative PainRetrospective StudiesChronic neuropathic painEndoscopic approachHernia repairMinimally invasive surgeryRetroperitoneal neurectomy

Identifiers

PMID36652009
PMCPMC9849289
OpenAlexW4317360660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.