Evidence map›Paper›PMID 36651989›Full record

ArticleEuropean journal of nutrition2023

Re-exploring the requirement of dietary iodine intake in Chinese female adults based on 'iodine overflow theory'.

Yajie Li, Jun Wang, Xiaobing Liu, Weidong Li, Deqian Mao, Jiaxi Lu, Xiuwei Li, Hongxing Tan, Yanyan Liu, Junan Yan and 4 more

Open access · hybridFull text read
In one paragraph

Article in European journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Yajie Li *Changzhi Medical College, No. 360, Jiefang East Street, Changzhi, 046000, Shanxi, People's Republic of China.ORCID http://orcid.org/0000-0002-6526-730X
Jun Wang *School of Food and Drug, Shenzhen Polytechnic, Shenzhen, 518055, Guangdong, People's Republic of China.
Xiaobing Liu *Chinese Center for Disease Control and Prevention, National Institute of Nutrition and Health, Key Laboratory of Trace Element Nutrition of National Health Commission, No. 29, Nanwei Road, Beijing, 100050, People's Republic of China.
Weidong LiChinese Center for Disease Control and Prevention, National Institute of Nutrition and Health, Key Laboratory of Trace Element Nutrition of National Health Commission, No. 29, Nanwei Road, Beijing, 100050, People's Republic of China.
Deqian MaoChinese Center for Disease Control and Prevention, National Institute of Nutrition and Health, Key Laboratory of Trace Element Nutrition of National Health Commission, No. 29, Nanwei Road, Beijing, 100050, People's Republic of China.
Jiaxi LuChinese Center for Disease Control and Prevention, National Institute of Nutrition and Health, Key Laboratory of Trace Element Nutrition of National Health Commission, No. 29, Nanwei Road, Beijing, 100050, People's Republic of China.
Xiuwei LiNational Reference Laboratory for iodine deficiency disorders, Chinese Center for Disease Control and Prevention, Beijing, 100050, People's Republic of China.
Hongxing TanShenzhen Center for Chronic Disease Control, No. 2021, Buxin Road, Shenzhen, 518020, Guangdong, People's Republic of China.
Yanyan LiuShenzhen Center for Chronic Disease Control, No. 2021, Buxin Road, Shenzhen, 518020, Guangdong, People's Republic of China.
Junan YanShenzhen Center for Chronic Disease Control, No. 2021, Buxin Road, Shenzhen, 518020, Guangdong, People's Republic of China.
Wei YuShenzhen Center for Chronic Disease Control, No. 2021, Buxin Road, Shenzhen, 518020, Guangdong, People's Republic of China.
Chongzheng GuoChangzhi Medical College, No. 360, Jiefang East Street, Changzhi, 046000, Shanxi, People's Republic of China.
Xiaoli LiuShenzhen Center for Chronic Disease Control, No. 2021, Buxin Road, Shenzhen, 518020, Guangdong, People's Republic of China.
Xiaoguang YangChinese Center for Disease Control and Prevention, National Institute of Nutrition and Health, Key Laboratory of Trace Element Nutrition of National Health Commission, No. 29, Nanwei Road, Beijing, 100050, People's Republic of China. xgyangcdc@163.com.
National Health and Family Planning Commission · CNShenzhen Nanshan Center for Chronic Disease Control · CNChangzhi Medical College · CNChinese Center For Disease Control and Prevention · CNShenzhen Polytechnic University · CN

Funding

National Natural Science Foundation of China 81872624Sanming Project of Medicine in Shenzhen SZSM201611017
6 · The paper itself

Abstract

purposeWe re-explored the basal iodine requirement based on healthy Chinese female and a new iodine overflow theory was proposed for iodine balance study.

methodsThirty-six Chinese healthy female adults (age 20.7 ± 1.1) were recruited for this study, which included 40 days low iodine depletion period and six stages of 30 days supplementation period. Uniform diets with low iodine were provided and the content of iodine in the diet was regulated by dairy products. The total iodine intake from food and the total iodine excretion through 24-h urine and staged feces were completely gathered and monitored. The incremental (Δ) intake and excretion over the range were calculated.

resultsThe iodine intake and excretion were 13.6 μg/day and 48.6 μg/day at the first stage, respectively. The incremental iodine intakes and excretions were 21.1 μg/day to 120.3 μg/day and 25.8 μg/day to 105.4 μg/day for the supplementation stages, respectively. According to the 'iodine overflow theory', the zero iodine balance (Δ iodine intake = Δ iodine excretion) derived from a mixed effect model indicated a mean iodine intake of 52.2 μg/d (1.0 μg/d kg). The RNI for iodine to healthy Chinese female adult was 73.1 μg/d (1.4 μg/d kg).

conclusionA daily iodine intake of 52.2 μg/d may meet the basal iodine requirement for healthy Chinese female adults, and Chinese female may need more than 20% iodine intake than male based on the 'iodine overflow theory'. The trial was registered at the Chinese Clinical Trial Registry in May 2018 (No: ChiCTR1800016184).

Indexed as

DietIodineEast Asian PeopleFecesFemaleHumansNutritional StatusYoung AdultIodineBalance studyChinese female adultsIncremental iodine excretionIncremental iodine intakeIodineIodine overflow

Identifiers

PMID36651989
PMCPMC10030447
OpenAlexW4317104885

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read92
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.