Evidence map›Paper›PMID 36651930›Full record

ArticleJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2024

Dentoskeletal effects of clear aligner vs twin block-a short-term study of functional appliances.

Elisabetta Cretella Lombardo, Roberta Lione, Lorenzo Franchi, Francesca Gaffuri, Cinzia Maspero, Paola Cozza, Chiara Pavoni

Registry-linked trialOpen access · hybridAbstract readComparative StudyControlled Clinical Trial
In one paragraph

Article in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07608406 (Evaluation of the Efficacy of Functional Therapy Using Modified Twin Block Versus Clear Twin Block in Class II Skeletal Patients), which is not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07608406 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of the Efficacy of Functional Therapy Using Modified Twin Block Versus Clear Twin Block in Class II Skeletal Patients: A Randomized Controlled Clinical Trial

TypeinterventionalSponsorUniversity of AleppoRan2026 to 2026Enrolled40ConditionsSkeletal Class II MalocclusionArmsModified Twin Block Appliance, Conventional Clear Twin Block Appliance
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Elisabetta Cretella LombardoDepartment of Systems Medicine, University of Rome 'Tor Vergata', Viale Oxford 81, 00133, Rome, Italy.
Roberta LioneDepartment of Dentistry, UNSBC, Tirana, Albania.
Lorenzo FranchiDepartment of Surgery and Translational Medicine, University of Florence, Florence, Italy.
Francesca GaffuriDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinco, Milan, Italy.
Cinzia MasperoDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinco, Milan, Italy.
Paola CozzaDepartment of Dentistry, UNSBC, Tirana, Albania.
Chiara PavoniDepartment of Systems Medicine, University of Rome 'Tor Vergata', Viale Oxford 81, 00133, Rome, Italy. chiarapavoni@libero.it.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITSaint Camillus International University of Health and Medical Sciences · ITUniversity of Florence · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe twin block (TB) is one of the most widely used functional appliances for the correction of class II malocclusions. Align Technology (San Jose, CA, USA) developed the Invisalign® mandibular advancement (MA) that replicates the mechanism of action of a functional appliance. The aim of this study was to compare the changes produced by the TB versus those by MA.

methodsThe records of 56 class II patients treated with the TB (TB group: n = 35) or the MA (MA group: n = 21) were compared to a control sample of 15 untreated class II subjects (UC2).

resultsThe TB and MA groups showed a significant reduction of the ANB angle, compared to the controls (TB group: -1.5°; MA group: -1.5°; UC2 group: +0.2°). For the Co-Gn values, the TB and MA groups showed significant differences when compared with the UC2 group with an increase of 8.4 mm in TB patients and of 8.3 mm in MA patients. The increase of the distance of Pg to the true vertical line (TVL) was the only measurement where significant differences between the three groups were found with a greater advancement of the soft tissue pogonion in the TB group compared with the MA group and the UC2 group (TB group: +3 mm; MA group: +0.9 mm; UC2 group: -1.6 mm). The angle between the palatal plane and mandibular plane revealed a more relevant reduction in the TB and MA groups. Both appliances were able to reduce overjet and vertical overbite values.

conclusionsTreatment with the MA and TB appliances produced a significant elongation of the mandible with an improvement in sagittal relationship, overjet, and vertical overbite and with good control of the vertical relationship. TB subjects showed a greater advancement of the soft tissue chin.

Indexed as

Malocclusion, Angle Class IIOrthodontic Appliance DesignOrthodontic Appliances, FunctionalAdolescentChildEquipment Failure AnalysisFemaleHumansMaleMandibular AdvancementOrthodontic Appliances, RemovableTreatment OutcomeClass II malocclusionMandibular advancementMandibular skeletal retrusionOrthodontic appliances, removableTwin block

Identifiers

PMID36651930
PMCPMC11358164
OpenAlexW4317212861

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.