Evidence map›Paper›PMID 36651781›Full record

ArticleMicrobiology spectrum2023

Standardization of SARS-CoV-2 Cycle Threshold Values: Multisite Investigation Evaluating Viral Quantitation across Multiple Commercial COVID-19 Detection Platforms.

Kenneth Gavina, Lauren C Franco, Christopher M Robinson, Weston Hymas, Guang-Sheng Lei, Will Sinclair, Tara Hall, John Carlquist, John-Paul Lavik, Christopher L Emery and 4 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kenneth GavinaDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0001-8358-5611
Lauren C FrancoDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Christopher M RobinsonDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0003-4086-4690
Weston HymasARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA.
Guang-Sheng LeiDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Will SinclairIntermountain Laboratory Services, Department of Pathology, Intermountain Healthcare, Salt Lake City, Utah, USA.
Tara HallIntermountain Laboratory Services, Department of Pathology, Intermountain Healthcare, Salt Lake City, Utah, USA.
John CarlquistIntermountain Laboratory Services, Department of Pathology, Intermountain Healthcare, Salt Lake City, Utah, USA.
John-Paul LavikDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Christopher L EmeryDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Phillip R HeatonDepartment of Pathology and Laboratory Medicine, Health Partners, Bloomington, Minnesota, USA.
David HillyardARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA.
Bert K LopransiIntermountain Laboratory Services, Department of Pathology, Intermountain Healthcare, Salt Lake City, Utah, USA.
Ryan F RelichDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0001-5889-1190

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The demand for testing during the coronavirus disease 2019 (COVID-19) pandemic has resulted in the production of several different commercial platforms and laboratory-developed assays for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This has created several challenges, including, but not limited to, the standardization of diagnostic testing, utilization of cycle threshold (

Indexed as

COVID-19Clinical Laboratory TechniquesCOVID-19 TestingHumansPandemicsReference StandardsSARS-CoV-2United StatesharmonizationquantitationSARS-CoV-2standardizationviral load

Identifiers

PMID36651781
PMCPMC9927101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.