Evidence map›Paper›PMID 36651543›Full record

ArticleActa pharmaceutica (Zagreb, Croatia)2022

Evaluation and molecular modelling of bis-Schiff base derivatives as potential leads for management of diabetes mellitus.

Safa Daoud, Samar Thiab, Taghreed M A Jazzazi, Tareq M A Al-Shboul, Saeed Ullah

Open access · goldAbstract read
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In one paragraph

Article in Acta pharmaceutica (Zagreb, Croatia), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Safa DaoudDepartment of Pharmaceutical Chemistry and Pharmacognosy Faculty of Pharmacy, Applied Science Private University, Amman, Jordan.
Samar ThiabDepartment of Pharmaceutical Chemistry and Pharmacognosy Faculty of Pharmacy, Applied Science Private University, Amman, Jordan.
Taghreed M A JazzaziDepartment of Chemistry, Yarmouk University, Irbid, Jordan.
Tareq M A Al-ShboulDepartment of Chemistry and Chemical Technology, Tafila Technical University Tafila, Jordan.
Saeed UllahH. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences University of Karachi, Karachi-75270 Pakistan.
Applied Science Private University · JOInternational Center for Chemical and Biological Sciences · PKTafila Technical University · JOYarmouk University · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing a medication to cure and manage diabetes mellitus complications is of interest in medicinal chemistry. Toward this end, six bis-biphenyl-salicylaldehyde Schiff base derivatives have been evaluated for their α-glucosidase inhibition, antiglycation and anti-inflammation potentials. Four compounds (compounds

Indexed as

AcarboseDiabetes Mellitusalpha-GlucosidasesGlycoside Hydrolase InhibitorsHumansMolecular Docking SimulationSchiff BasesStructure-Activity RelationshipAcarbosealpha-GlucosidasesGlycoside Hydrolase InhibitorsSchiff Basesbis-Schiff basesdiabetes mellitusdocking studyglycationpostprandial hyperglycemiaα-glucosidase

Identifiers

PMID36651543
OpenAlexW4224096454

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.