ArticleThe journal of nutrition, health & aging2023
The Association between Air Pollutants Exposure with Pre- and Hypertension by Vitamin C Intakes in Korean Adults: A Cross-Sectional Study from the 2013-2016 Korea National Health and Nutrition Examination.
Article in The journal of nutrition, health & aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 6 citations in OpenAlex.
- The effect of the urban built environment on the prevalence rate of chronic diseases in the community neighborhood level: a case study in Qingdao, China.BMC public health · 2025Article
- Physical activity in the relationship between multiple air pollutants exposure and risk of hypertension: a prospective cohort study in China.Scientific reports · 2025Article
- Causal Relationship Between Air Pollutants and Blood Pressure Phenotypes: A Mendelian Randomization Study.Global heart · 2025Article
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesOxidative stress and systemic inflammation are the main pathways by which air pollutants cause hypertension (HTN). Vitamin C intake may reduce the risk of HTN caused by air pollutants. This study aimed to investigate the association between air pollutants and pre-HTN and HTN in Korean adults and whether these associations were modified by vitamin C intake, using data from the 2013-2016 Korean National Health and Nutrition Examination Survey (KNHANES).
designCross-sectional study.
settingThis study used data from the KNHANES VI (2013-2015) and VII (2016) along with the data from the annual air pollution report of the Ministry of Environment.
participantsWe included 11,866 adults who had responded to a semi-food frequency questionnaire. MEASUREMENTS: We used survey logistic regression models to evaluate the association of ambient PM10, SO2, NO2, CO, and O3 with pre-HTN and HTN according to vitamin C intake.
resultsAfter adjusting for potential covariates, exposure to ambient PM10, SO2, NO2, and CO was significantly associated with a high prevalence of pre-HTN and HTN, whereas exposure to O3 was significantly associated with a low prevalence of pre-HTN and HTN. In particular, as the air pollutant scores increased (severe air pollution), the prevalence of pre-HTN and HTN increased in a dose-dependent manner (highest score vs. lowest score, OR=1.85, 95% CI=1.39-2.46, p for trend <.0001). However, these associations were found to be pronounced in adults with low vitamin C intake (highest score vs. lowest score, OR=2.30, 95% CI=1.50-3.54, p for trend <.0001), whereas the statistical significance disappeared for adults with high vitamin C intake (highest score vs. lowest score, OR=1.40, 95% CI=0.93-2.12, p for trend=0.007).
conclusionExposure to air pollutants such as PM10, SO2, NO2, and CO may increase the prevalence of pre-HTN and HTN among Korean adults. In addition, a high intake of vitamin C may help prevent pre-HTN and HTN caused by air pollutants.
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