Evidence map›Paper›PMID 36651271›Full record

ReviewPharmacogenomics2023

The frequency of rs2231142 in

Khalifa Alrajeh, Youssef M Roman

Open access · greenAbstract readReview
In one paragraph

Review in Pharmacogenomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Retrospective Evaluation of the Impact ofJournal of personalized medicine · 2025
    Article
  4. Article
  5. Major Allele Frequencies inJournal of personalized medicine · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. The frequency of majorPharmacogenomics · 2023
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Khalifa AlrajehDepartment of Pharmacotherapy & Outcome Science, Virginia Commonwealth University School of Pharmacy, 410 N 12th Street, Richmond, VA 23298, USA.ORCID 0000-0003-4406-1473
Youssef M RomanDepartment of Pharmacotherapy & Outcome Science, Virginia Commonwealth University School of Pharmacy, 410 N 12 Street, Richmond, VA 23298, USA.ORCID 0000-0002-0613-5534
Virginia Commonwealth University · US

Funding

UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Peter R Hoffmann · 2012 to 2026
$60.3M
RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MOKUAU, NOREEN, SHIRAMIZU, BRUCE T · 2012 to 2018
$21.1M
RESEARCH DESIGN, BIOSTATISTICS AND RESEARCH ETHICS COREG12MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI BERRY, MARLA J · 2012 to 2016
$13.0M
NIGMS NIH HHS P20 GM103466NIMHD NIH HHS G12 MD007601NIMHD NIH HHS U54 MD007584
6 · The paper itself

Abstract

Statins are widely used medications for the primary and secondary prevention of cardiovascular diseases. Statin-induced musculoskeletal symptoms are the primary adverse drug events contributing to poor adherence to lipid-lowering therapy. Rosuvastatin is characterized by interindividual differences in systemic exposure among different patient population subgroups. The missense variant

Indexed as

ATP-Binding Cassette TransportersHydroxymethylglutaryl-CoA Reductase InhibitorsATP Binding Cassette Transporter, Subfamily G, Member 2GenotypeHumansNeoplasm ProteinsPolymorphism, Single NucleotideRosuvastatin CalciumABCG2 protein, humanATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily G, Member 2Hydroxymethylglutaryl-CoA Reductase InhibitorsNeoplasm ProteinsRosuvastatin CalciumABCG2adverse drug reactionAsian ancestrycardiovascular pharmacogenomicsdrug transportersdyslipidemiaFilipinosstatins

Identifiers

PMID36651271
PMCPMC9979151
OpenAlexW4317209295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.