ArticleInternational wound journal2023
Status and influencing factors of lower limb amputation in patients with diabetic foot ulcer.
Article in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and risk factors for amputation in Chinese patients with diabetic foot ulcers: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Integrative biomarker analysis in diabetic foot: lipids, cellular integrity, and hydration balance.Diabetology & metabolic syndrome · 2025Article
- An interpreting machine learning models to predict amputation risk in patients with diabetic foot ulcers: a multi-center study.Frontiers in endocrinology · 2025Article
- RETRACTED: Effects of comprehensive nursing intervention in patients with diabetic foot ulcers: A meta-analysis.International wound journal · 2024Article
- Peripheral artery disease mediating the effect of metabolic syndrome related diseases on lower limb ulcers: Mendelian randomization analysis.Frontiers in endocrinology · 2024Article
- Risk Factors Associated with Amputation for Patients with Diabetic Foot Ulcers: A Retrospective Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Lipid Profile Paradox: Investigating Improved Lipid Levels in Diabetic Mellitus Patients with Foot Ulcer Infections-A Prospective Descriptive Study.Diagnostics (Basel, Switzerland) · 2023Article
- Status and influencing factors of lower limb amputation in patients with diabetic foot ulcer.International wound journal · 2023Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the influencing factors of lower limb amputation in patients with diabetic foot ulcers. Patients with diabetic foot ulcers who were hospitalised in a tertiary general hospital in Guizhou Province from January 2019 to March 2022 were retrospectively collected. Sociological information of the general population, comorbidities, laboratory-related indicators, and information on the specialty situation, using univariate analysis and multifactor analysis, compared the influencing factors of amputation and non-amputee patients. A total of 205 patients with diabetic foot and 69 ampute patients (33.7%) were enrolled. The univariate analysis found that the decrease in HDL cholesterol levels was associated with the occurrence of lower extremity amputation, and logistic stepwise regression analysis showed that HDL-C was inversely correlated with the amputation rate of patients with diabetic foot ulcers, and the risk of amputation at low levels of HDL-C was 2.452 times higher than that of high-level HDL-C (95% CI: 1.105-5.846). Decreased HDL cholesterol levels are an independent predictor of amputation in patients with diabetic foot ulcers.
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