Evidence map›Paper›PMID 36650854›Full record

ArticleOpen veterinary journal

Evaluation of setup errors of immobilization device for radiation therapy in companion animals.

Toshie Iseri, Nanami Hira, Yoshinori Tanabe, Hiro Horikirizono, Hiroshi Sunahara, Harumichi Itoh, Yuki Nemoto, Kazuhito Itamoto, Kenji Tani, Munekazu Nakaichi

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Article in Open veterinary journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Toshie IseriFaculty of Agriculture, Animal Medical Emergency Center, Tokyo University of Agriculture and Technology, Tokyo, Japan.
Nanami HiraFacilty of Health Sciences, Okayama University Medical School, Okayama, Japan.
Yoshinori TanabeFaculty of Medicine, Graduate School of Health Sciences, Okayama University, Okayama, Japan.
Hiro HorikirizonoJoint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.
Hiroshi SunaharaJoint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.
Harumichi ItohJoint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.
Yuki NemotoJoint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.
Kazuhito ItamotoJoint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.
Kenji TaniJoint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.
Munekazu NakaichiJoint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intensity-modulated radiotherapy (IMRT), which allows generating steep dose gradients, is a beneficial treatment for companion animals with adjacent target and risk organs. IMRT is essential for high setup accuracy for avoiding overdose to risk organs, and optimal radiotherapy is important for evaluating the setup accuracy of companion animals. Aim: To use an immobilization device to evaluate setup errors in radiotherapy for companion animals. Methods: We calculated setup errors in radiotherapy for 386 animals (dogs and cats; 3,261 registration images) that underwent radiotherapy between 2016 and 2022. The companion animals were immobilized with a customized bite block and vacuum lock device. A quantile-quantile plot with 95% confidence interval (CI) was used to evaluate the histogram of the setup errors, and the systematic and random setup errors were calculated for each region (brain, head and neck, chest and abdomen, pelvis, and spine). Results: The setup error in each direction presented an extremely narrow-interval histogram, with the following lower and upper 95% CIs: cranial-caudal (-0.08, -0.06 cm); left-right (-0.04, -0.02 cm); and dorsal-ventral (-0.13, -0.11 cm). The mean systematic setup error was 0.16 cm (range: 0.12-0.36 cm), and the random error was 0.15 cm (range: 0.08-0.34 cm). The pelvis showed the highest systematic and random setup errors (mean: 0.36 and 0.23 cm, respectively). Conclusion: The use of an immobilization device enables highly accurate radiotherapy for companion animals (95% CI < 0.15 cm).

Indexed as

Cat DiseasesDog DiseasesHead and Neck NeoplasmsAnimalsCatsDogsImmobilizationPetsRadiotherapy DosageRadiotherapy Planning, Computer-AssistedCompanion animalsHead and neckImmobilization deviceRadiation therapySetup error

Identifiers

PMID36650854
PMCPMC9805779

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.