Evidence map›Paper›PMID 36650705›Full record

ArticleNeurogastroenterology and motility2023

Positive psychological well-being: A novel concept for improving symptoms, quality of life, and health behaviors in irritable bowel syndrome.

Elizabeth N Madva, Lauren E Harnedy, Regina M Longley, Alexandra Rojas Amaris, Crystal Castillo, Marie D Bomm, Helen Burton Murray, Kyle Staller, Braden Kuo, Laurie Keefer and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Neurogastroenterology and motility, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Effect of Cognitive Behavior Therapy on the Mental Health of Patients With Irritable Bowel Syndrome: A Systematic Review.Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Irritable Bowel Syndrome and Resilience.Journal of clinical medicine · 2023
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Elizabeth N MadvaHarvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-2194-2032
Lauren E HarnedyDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
Regina M LongleyDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
Alexandra Rojas AmarisDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
Crystal CastilloDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
Marie D BommHarvard Medical School, Boston, Massachusetts, USA.
Helen Burton MurrayHarvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-2059-3256
Kyle StallerHarvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-4925-4290
Braden KuoHarvard Medical School, Boston, Massachusetts, USA.
Laurie KeeferMount Sinai Hospital School of Medicine, Psychiatry and Gastroenterology, New York, New York, USA.
Jeff C HuffmanHarvard Medical School, Boston, Massachusetts, USA.
Christopher M CelanoHarvard Medical School, Boston, Massachusetts, USA.
Harvard University · USMassachusetts General Hospital · USMount Sinai Hospital · US

Funding

New England Gastropareis Consortium: Neurobiology of GastroparesisU01DK112193 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Helen Burton Murray, Braden Kuo · 2016 to 2026
$4.8M
A novel behavioral intervention to promote adherence in heart failureR01HL155301 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI CELANO, CHRISTOPHER M · 2021 to 2025
$3.8M
Pragmatic collaborative care for cardiac inpatients with depression or anxietyR01HL133149 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HUFFMAN, JEFF C · 2017 to 2021
$3.8M
TRANSLUMBOSACRAL NEUROMODULATION THERAPY FOR FECAL INCONTINENCE: RANDOMIZED TRIALR01DK121003 · NIDDK · AUGUSTA UNIVERSITY · PI KUO, BRADEN, RAO, SATISH SC · 2019 to 2023
$2.6M
A Biobehavioral Approach to Understand Problematic Avoidant/Restrictive Eating in Adults with Functional DyspepsiaK23DK131334 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BURTON MURRAY, HELEN · 2021 to 2025
$1.1M
The Role of Fiber in the Etiopathogenesis of Fecal IncontinenceK23DK120945 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI STALLER, KYLE · 2020 to 2024
$1.0M
NHLBI NIH HHS R01 HL133149NHLBI NIH HHS R01 HL155301NIDDK NIH HHS K23 DK120945NIDDK NIH HHS K23 DK131334NIDDK NIH HHS R01 DK121003NIDDK NIH HHS U01 DK112193
6 · The paper itself

Abstract

backgroundThough a growing body of research suggests that greater positive psychological well-being in irritable bowel syndrome (IBS) may be protective, existing brain-gut behavior therapies primarily target negative psychological factors. Little is known about how positive psychological factors in IBS relate to IBS symptoms, health-related quality of life (HRQoL), or adherence to key health behaviors, such as physical activity and diet modification. Accordingly, per the ORBIT model of behavioral treatment development for chronic diseases, we explored potential connections between psychological constructs and IBS symptoms, health behavior engagement (physical activity and dietary modification), and HRQoL in a qualitative study to inform the development of a novel brain-gut behavior therapy.

methodsParticipants with IBS completed self-report assessments and semi-structured phone interviews about relationships between positive and negative psychological constructs, IBS symptoms, health behavior engagement, and HRQoL. KEY

resultsParticipants (n = 23; 57% female) ranged in age from 25 to 79 (mean age = 54). IBS subtypes were similarly represented (IBS-diarrhea [n = 8], IBS-constipation [n = 7], and IBS-mixed [n = 8]). Participants described opposing relationships between positive and negative psychological constructs, IBS symptoms, health behavior engagement, and HRQoL, respectively, such that experiencing positive constructs largely mitigated IBS symptoms, boosted health behavior participation, and improved HRQoL, and negative constructs exacerbated symptoms, reduced health behavior participation, and worsened HRQoL. CONCLUSIONS AND INFERENCES: Participants with IBS linked greater positive psychological well-being to moderated IBS symptoms and better HRQoL and health behavior participation. An intervention to cultivate greater well-being may be a novel way to mitigate IBS symptoms, boost health behavior participation, and improve HRQoL in IBS.

Indexed as

Irritable Bowel SyndromeFemaleHealth BehaviorHumansMaleMiddle AgedPsychological Well-BeingQuality of LifeSurveys and Questionnairesfunctional gastrointestinal disordersirritable bowel syndromepsychology, positivepsychosomatic medicine

Identifiers

PMID36650705
PMCPMC10033392
OpenAlexW4317036820

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.