Evidence map›Paper›PMID 36650675›Full record

ArticleEarly intervention in psychiatry2023

Residential instability during adolescence predicts earlier age at onset of psychosis: The moderating role of extraversion.

Benson S Ku, Elaine F Walker, Benjamin G Druss, Camille R Murray, Michael T Compton

Open access · greenAbstract read
In one paragraph

Article in Early intervention in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Urbanicity and psychotic disorders: Facts and hypotheses.Dialogues in clinical neuroscience · 2023
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Benson S KuDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0001-6994-8770
Elaine F WalkerDepartment of Psychology, Emory University, Atlanta, Georgia, USA.
Benjamin G DrussDepartment of Health Policy and Management, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Camille R MurrayDepartment of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Michael T ComptonNew York State Psychiatric Institute, New York, New York, USA.ORCID 0000-0001-6835-2502
Emory University · USNew York Psychoanalytic Society and Institute · US

Funding

Emory Psychiatry Clinical Scientist Training Program (CSTP)R25MH101079 · NIMH · EMORY UNIVERSITY · PI GOLDSMITH, DAVID RYAN, MILLER, ANDREW H · 2014 to 2025
$1.9M
First-Episode Psychosis and Pre-Onset Cannabis UseR01MH081011 · NIMH · GEORGE WASHINGTON UNIVERSITY · PI MYERS, NEELY A · 2008 to 2012
$1.7M
Impact of Neighborhood Characteristics on Conversion to Psychosis among Youth at Clinical High Risk for PsychosisK23MH129684 · NIMH · EMORY UNIVERSITY · PI Benson Ku · 2022 to 2026
$970k
NIMH NIH HHS K23 MH129684NIMH NIH HHS R01 MH081011NIMH NIH HHS R25 MH101079
6 · The paper itself

Abstract

introductionResidential instability (RI) during adolescence is associated with poor health outcomes. Also, extraversion has been shown to be a moderator of these associations. However, the associations between RI, extraversion, and age at onset of psychosis (AOP) remain unknown.

methodsData were collected from patients with first-episode psychosis (FEP). Linear regression models assessed the association between RI during adolescence and AOP. Extraversion was tested as a moderator using the interaction term RI-by-extraversion.

resultsAmong 89 participants with FEP, both RI (adjusted β = -.278, p = .006) and the interaction term RI-by-extraversion (adjusted β = .290, p < .001) were associated with earlier AOP. Stratified analyses showed that RI was only significantly associated with earlier AOP among those with low extraversion (adjusted β = -.598, p < .001).

conclusionsRI predicted earlier AOP and this association was moderated by extraversion. These findings suggest that extraversion may buffer the negative relationship between RI and AOP. Future research should replicate these findings.

Indexed as

Psychotic DisordersSchizophreniaAdolescentAge of OnsetExtraversion, PsychologicalHumansLinear Modelsage at onsetextraversionpsychosisresidential instabilityschizophrenia

Identifiers

PMID36650675
PMCPMC10175105
OpenAlexW4317036748

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.