Evidence map›Paper›PMID 36650669›Full record

ArticleJournal of diabetes2023

Evaluating the role of time in range as a glycemic target during short-term intensive insulin therapy in patients with newly diagnosed type 2 diabetes.

Liehua Liu, Weijian Ke, Lijuan Xu, Hai Li, Juan Liu, Xuesi Wan, Jianbin Liu, Wanping Deng, Xiaopei Cao, Haipeng Xiao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

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  7. Time in target range for systolic blood pressure and glucose with cardiovascular disease and all-cause mortality risks.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Liehua LiuDepartment of Endocrinology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Weijian KeDepartment of Endocrinology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Lijuan XuDepartment of Endocrinology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Hai LiDepartment of Endocrinology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Juan LiuDepartment of Endocrinology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Xuesi WanDepartment of Endocrinology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Jianbin LiuEndocrinology Department, Eastern Health, Melbourne, Victoria, Australia.
Wanping DengDepartment of Endocrinology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Xiaopei CaoDepartment of Endocrinology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Haipeng XiaoDepartment of Endocrinology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.ORCID https://orcid.org/0000-0002-4188-336X
Yanbing LiDepartment of Endocrinology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.ORCID https://orcid.org/0000-0003-3782-9210
Sun Yat-sen University · CN

Funding

National Key R&D Program of China 2018YFC1314100the Key-Area Research and Development Program of Guangdong Province 2019B020230001the National Natural Science Fund of China 81800716the National Natural Science Fund of China 81870557the Natural Science Fund of Guangdong province 2016A030313239the science and technology program of Guangzhou 202002020053
6 · The paper itself

Abstract

backgroundTight glycemic control during short-term intensive insulin therapy (SIIT) is critical for inducing diabetes remission in patients with newly diagnosed type 2 diabetes (T2D). This work aimed to investigate the role of time in range (TIR) during SIIT as a novel glycemic target by predicting clinical outcomes.

methodsSIIT was given to 116 patients with newly diagnosed T2D, with daily eight-point capillary glucose monitored. Glycemic targets (fasting/premeal glucose, 3.9-6.0 mmol/L; 2 h postprandial blood glucose, 3.9-7.8 mmol/L) were achieved and maintained for 2 weeks. TIR

resultsTIR

conclusionsThese findings advocate TIR

Indexed as

Diabetes Mellitus, Type 2HyperglycemiaBlood GlucoseHumansHypoglycemic AgentsInsulinBlood GlucoseHypoglycemic AgentsInsulin2型糖尿病。newly diagnosedremissionshort-term intensive insulin therapytime in rangetype 2 diabetes初诊短期胰岛素强化治疗缓解葡萄糖在目标范围内时间

Identifiers

PMID36650669
PMCPMC9934958
OpenAlexW4317358874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.