SynthesisCNS neuroscience & therapeutics2023
Effectiveness and safety of ventriculoperitoneal shunt versus lumboperitoneal shunt for communicating hydrocephalus: A systematic review and meta-analysis with trial sequential analysis.
Synthesis in CNS neuroscience & therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Lumboperitoneal versus ventriculoperitoneal shunt surgery in adult post-hemorrhagic hydrocephalus: A systematic review and meta-analysis.Neurosurgical review · 2026Pooled it
- Endovascular Treatment of Hydrocephalus: A Systematic Literature Review.Clinical neuroradiology · 2026Pooled it
- Advancing treatment strategies for idiopathic normal pressure hydrocephalus: a systematic review on studies comparing ventricular and lumbo-peritoneal shunts.Neurosurgical review · 2025Pooled it
- Morbidity and etiology-based success rate of combined endoscopic ventriculostomy and choroid plexus cauterization: a systematic review and meta-analysis of 1918 infants.Neurosurgical review · 2023Pooled it
- Effectiveness and safety of ventriculoperitoneal shunt versus lumboperitoneal shunt for communicating hydrocephalus: A systematic review and meta-analysis with trial sequential analysis.CNS neuroscience & therapeutics · 2023Pooled it
- Comparative efficacy and safety of surgical interventions for communicating hydrocephalus: a systematic review and network meta-analysis of randomized controlled trials.Frontiers in neurologyPooled it
- Prognostic Significance of SIRI and SII in Posttraumatic Hydrocephalus Following Traumatic Brain Injury.Asian journal of neurosurgery · 2026Article
- Cerebrospinal Fluid Shunts: An Updated Radiologic Review of Devices, Malfunctions, and Complications.Korean journal of radiology · 2026Review
- Continuum of Irreversible and Potentially Reversible Traumatic Brain Injury Sequelae: Axonal Injury and Hydrocephalus.Korean journal of neurotrauma · 2026Review
- Clinical Outcomes of Lumboperitoneal Shunt Surgery for Normal Pressure Hydrocephalus : A 5-Year Single-Center Retrospective Study of Patients with at Least 1 Year of Follow-Up.Journal of Korean Neurosurgical Society · 2026Article
- Intraoperative cone-beam CT for real-time quality control in CSF shunt surgery: a prospective workflow study.Brain & spine · 2026Article
- Meningeal lymphatic drainage: novel insights into central nervous system disease.Signal transduction and targeted therapy · 2025Review
- Navigating challenges in hydrocephalus following intraventricular hemorrhage: a comprehensive review of current evidence.Frontiers in neurology · 2025Review
- The contribution of cerebral small vessel disease in idiopathic normal pressure hydrocephalus: Insights from a prospective cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Lumboperitoneal shunting as a rescue strategy in the management of complex cranial wound conditions.Brain & spine · 2025Article
- Analysis of risk factors for delayed intracranial hemorrhage following ventriculoperitoneal shunt surgery and construction of a nomogram model.Frontiers in neurology · 2025Article
- Rare Complications of Lumboperitoneal Shunts: Abdominal Cerebrospinal Fluid Pseudocysts in Adults.Cureus · 2025Article
- Relationship between the volume of ventricles, brain parenchyma and neurocognition in children after hydrocephalus treatment.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Intraventricular Tigecycline Therapy for Ventriculoperitoneal Shunt-Related Septic Shock Caused by Colistin-ResistantInfectious diseases & clinical microbiology · 2024Article
- Primary adrenal insufficiency developed 22 years after the diagnosis of light and heavy chain deposition disease: a case report.CEN case reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe current standard surgical treatment for cerebrospinal fluid diversion is a ventriculoperitoneal shunt (VPS) implantation. Lumboperitoneal shunts (LPS) are an alternative treatment for communicating hydrocephalus. Prior studies comparing these two included a limited number of participants.
methodsWe performed a meta-analysis determined the treatment failure, complications and effectiveness of lumboperitoneal shunt for communicating hydrocephalus. We reviewed studies with clinical and imaging diagnoses of communicating hydrocephalus, all causes and subtypes of communicating hydrocephalus, and studies that analyzed the primary and secondary outcomes listed below. We included randomized controlled trials (RCTs), non-RCTs and retrospective studies. We performed the meta-analysis in R, using a random-effects model and reporting 95% confidence intervals.
resultsData from 25 studies, including 3654 patients, were analyzed. The total complication rates were 12.98% (188/1448) for lumboperitoneal shunt and 23.80% (398/1672) for ventriculoperitoneal shunt. The odds ratio for lumboperitoneal shunt versus ventriculoperitoneal shunt complication rates was 0.29 (95% CI 0.19 to 0.45, p < 0.0001), and the I
conclusionsThis analysis demonstrated that lumboperitoneal shunt is a safe and equally effective choice for treating communicating hydrocephalus. More studies are needed to confirm the safety of lumboperitoneal shunt.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.