Evidence map›Paper›PMID 36650581›Full record

ArticleMolecular brain2023

Axonal membrane stretch suppresses neuronal excitability by activating mechanosensitive K2P channels at the node of Ranvier.

Hirosato Kanda, Koichi Noguchi, Yi Dai

Open access · goldAbstract read
In one paragraph

Article in Molecular brain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hirosato KandaSchool of Pharmacy, Hyogo Medical University, Kobe, Hyogo, 650-8530, Japan. kanda@hyo-med.ac.jp.ORCID 0000-0003-2547-9073
Koichi NoguchiLaboratory of Basic Pain Research, Hyogo Medical University, Kobe, Hyogo, 650-8530, Japan.
Yi DaiSchool of Pharmacy, Hyogo Medical University, Kobe, Hyogo, 650-8530, Japan.
Hyogo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saltatory conduction is the propagation of action potentials along myelinated nerves, which enables fast propagation through the node of Ranvier. Recently, we demonstrated that K2P channels, TWIK-related K

Indexed as

Potassium Channels, Tandem Pore DomainStress, MechanicalAction PotentialsAnimalsArachidonic AcidAxonsNeuronsPotassium ChannelsRatsArachidonic AcidKcnk4 protein, ratpotassium channel protein TREK-1Potassium ChannelsPotassium Channels, Tandem Pore DomainAction potentialMembrane stretchNode of RanvierSingle-channel activityTwo-pore-domain potassium channels

Identifiers

PMID36650581
PMCPMC9843873
OpenAlexW4317103228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.