Evidence map›Paper›PMID 36650496›Full record

ArticleBMC musculoskeletal disorders2023

Automatic segmentation of human knee anatomy by a convolutional neural network applying a 3D MRI protocol.

Carl Petter Skaar Kulseng, Varatharajan Nainamalai, Endre Grøvik, Jonn-Terje Geitung, Asbjørn Årøen, Kjell-Inge Gjesdal

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carl Petter Skaar KulsengSunnmøre MR-klinikk, Langelandsvegen 15, Ålesund, 6010, Norway.
Varatharajan NainamalaiNorwegian University of Science and Technology, Larsgaardvegen 2, Ålesund, 6025, Norway.
Endre GrøvikNorwegian University of Science and Technology, Høgskoleringen 5, Trondheim, 7491, Norway.
Jonn-Terje GeitungSunnmøre MR-klinikk, Langelandsvegen 15, Ålesund, 6010, Norway. j.t.geitung@medisin.uio.no.
Asbjørn ÅrøenDepartment of Orthopedic Surgery, Institute of Clinical Medicine, Akershus University Hospital, Problemveien 7, Oslo, 0315, Norway.
Kjell-Inge GjesdalSunnmøre MR-klinikk, Langelandsvegen 15, Ålesund, 6010, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo study deep learning segmentation of knee anatomy with 13 anatomical classes by using a magnetic resonance (MR) protocol of four three-dimensional (3D) pulse sequences, and evaluate possible clinical usefulness.

methodsThe sample selection involved 40 healthy right knee volumes from adult participants. Further, a recently injured single left knee with previous known ACL reconstruction was included as a test subject. The MR protocol consisted of the following 3D pulse sequences: T1 TSE, PD TSE, PD FS TSE, and Angio GE. The DenseVNet neural network was considered for these experiments. Five input combinations of sequences (i) T1, (ii) T1 and FS, (iii) PD and FS, (iv) T1, PD, and FS and (v) T1, PD, FS and Angio were trained using the deep learning algorithm. The Dice similarity coefficient (DSC), Jaccard index and Hausdorff were used to compare the performance of the networks.

resultsCombining all sequences collectively performed significantly better than other alternatives. The following DSCs (±standard deviation) were obtained for the test dataset: Bone medulla 0.997 (±0.002), PCL 0.973 (±0.015), ACL 0.964 (±0.022), muscle 0.998 (±0.001), cartilage 0.966 (±0.018), bone cortex 0.980 (±0.010), arteries 0.943 (±0.038), collateral ligaments 0.919 (± 0.069), tendons 0.982 (±0.005), meniscus 0.955 (±0.032), adipose tissue 0.998 (±0.001), veins 0.980 (±0.010) and nerves 0.921 (±0.071). The deep learning network correctly identified the anterior cruciate ligament (ACL) tear of the left knee, thus indicating a future aid to orthopaedics.

conclusionsThe convolutional neural network proves highly capable of correctly labeling all anatomical structures of the knee joint when applied to 3D MR sequences. We have demonstrated that this deep learning model is capable of automatized segmentation that may give 3D models and discover pathology. Both useful for a preoperative evaluation.

Indexed as

Anterior Cruciate Ligament InjuriesImaging, Three-DimensionalKneeKnee JointAdultHumansMagnetic Resonance ImagingNeural Networks, ComputerDeep learningKnee images segmentationMagnetic Resonance ImagingMusculoskeletalVisualization

Identifiers

PMID36650496
PMCPMC9847207

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.