SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2023
Outcomes of Intraoperative Pyloric Drainage on Delayed Gastric Emptying Following Esophagectomy: A Systematic Review and Meta-analysis.
Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Prophylactic pyloric drainage for prevention of delayed gastric conduit emptying following Ivor Lewis esophagectomy: a systematic review with exploratory synthesis.Surgical endoscopy · 2026Pooled it
- Incidence of delayed gastric conduit emptying in patients undergoing esophagectomy: a systematic review and meta‑analysis.Esophagus : official journal of the Japan Esophageal Society · 2025Pooled it
- Prophylactic Pyloric Dilatation and its Impact on Early Delayed Gastric Conduit Emptying and Pneumonia Post-esophagectomy: A Multi-centre Cohort Study.Annals of surgical oncology · 2026Article
- Applicability and results of the consensus definition of delayed gastric conduit emptying after esophagectomy.Langenbeck's archives of surgery · 2026Article
- Comparison of Endoscopic and Intraoperative Approaches in the Management of Delayed Gastric Conduit Emptying After Minimally Invasive Esophagectomy: A Single-Center Retrospective Analysis.Journal of clinical medicine · 2026Article
- Experience with H anastomosis and its perioperative management protocol in minimally invasive esophagectomy: a propensity score-matched comparison with stapled non-enhanced recovery after surgery pathway.Journal of thoracic disease · 2026Article
- Mastering esophageal cancer imaging: what radiologists need to know.Abdominal radiology (New York) · 2025Review
- Article
- Effect of pyloroplasty on clinical outcomes following esophagectomy.Surgical endoscopy · 2025Article
- Clinical implementation of minimally invasive esophagectomy.BMC surgery · 2024Article
- Article
- Intra-operative pyloric BOTOX injection versus pyloric surgery for prevention of delayed gastric emptying after esophagectomy.Surgical endoscopy · 2024Article
- Surgical revision of the postesophagectomy gastric conduit to address poor emptying.JTCVS techniques · 2024Article
- Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntraoperative pyloric drainage in esophagectomy may reduce delayed gastric emptying (DGE) but is associated with risk of biliary reflux and other complications. Existing evidence is heterogenous. Hence, this meta-analysis aims to compare outcomes of intraoperative pyloric drainage versus no intervention in patients undergoing esophagectomy.
methodsPubMed/MEDLINE, Embase, Web of Science, and the Cochrane were searched from inception up to July 2022. Exclusion criteria were lack of objective evidence (e.g., symptoms of nausea or vomiting) of DGE. The primary outcome was incidence of DGE. Secondary outcomes were incidence of pulmonary complications, bile reflux, anastomotic leak, operative time, and mortality.
resultsThere were nine studies including 1164 patients (pyloric drainage n = 656, no intervention n = 508). Intraoperative pyloric drainage included pyloroplasty (n = 166 (25.3%)), pyloromyotomy (n = 214 (32.6%)), botulinum toxin injection (n = 168 (25.6%)), and pyloric dilatation (n = 108 (16.5%)). Pyloric drainage is associated with reduced DGE (odds ratio (OR): 0.54, 95% confidence interval (CI): 0.39-0.74, I
conclusionsPyloric drainage in esophagectomy reduces DGE but has similar post-operative outcomes. Further prospective studies should be carried out to compare various pyloric drainage techniques and its use in esophagectomy, especially minimally-invasive esophagectomy.
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