ArticleScientific reports2023
Comparing the accuracy of ultrasound-based measurements of the cervical vagus nerve.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- Determinants of carotid sinus hypersensitivity in patients with suspected reflex syncope.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Ultrasonographic measurement of cross-sectional area of the vagus nerve in patients with diabetic neuropathy: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- Laterality, sexual dimorphism, and human vagal projectome heterogeneity shape neuromodulation to vagus nerve stimulation.Communications biology · 2024Article
- Evaluating Diagnostic Ultrasound of the Vagus Nerve as a Surrogate Marker for Autonomic Neuropathy in Diabetic Patients.Medicina (Kaunas, Lithuania) · 2023Article
- Enlarged cross-sectional area of the left vagus nerve in patients with major depressive disorder.Frontiers in psychiatry · 2023Article
- A standardized, surgically relevant map for emergence of organ-specific branches from the human vagus nerve.Brain stimulationArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vagus nerve stimulation (VNS) has become a promising therapy especially for drug resistant epilepsy and other pathologies. Side effects or missing therapeutic success are observed due to cuff electrodes that are too narrow or too wide. Preoperative high-resolution ultrasound is used to evaluate the size of the cervical vagus nerve (CVN) to estimate the size of cuff electrodes for VNS. It remains unclear how precise ultrasound reflects the CVN dimensions, which has been the objective of this study. CVN cross-sections and diameters were investigated in 23 sides from 12 bodies, using ultrasound, histology, and CVN casting in situ as a reference. Morphometric data were obtained including fascicle count and nerve composition in histology. CVN yielded significant side-, age-, and BMI-related differences. CVN cross-sections were smaller in ultrasound when compared to casting and histology (1.5 ± 0.4 vs. 3.1 ± 0.9 vs. 2.3 ± 0.7 mm
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