Evidence map›Paper›PMID 36650051›Full record

ArticleGenome research2023

A temporal in vivo catalog of chromatin accessibility and expression profiles in pineoblastoma reveals a prevalent role for repressor elements.

Salam Idriss, Mohammad Hallal, Abdullah El-Kurdi, Hasan Zalzali, Inaam El-Rassi, Erik A Ehli, Christel M Davis, Philip E D Chung, Deena M A Gendoo, Eldad Zacksenhaus and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Salam Idriss *Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Beirut 1107 2020, Lebanon.
Mohammad Hallal *Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Beirut 1107 2020, Lebanon.
Abdullah El-Kurdi *Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Beirut 1107 2020, Lebanon.
Hasan ZalzaliDepartment of Pediatric and Adolescent Medicine, American University of Beirut, Beirut 1107 2020, Lebanon.
Inaam El-RassiBiomedical Engineering Program, American University of Beirut, Beirut 1107 2020, Lebanon.
Erik A EhliAvera Institute for Human Genetics, Sioux Falls, South Dakota 57108, USA.
Christel M DavisAvera Institute for Human Genetics, Sioux Falls, South Dakota 57108, USA.
Philip E D ChungToronto General Research Institute, University Health Network, Toronto, Ontario M5G 1L7, Canada.
Deena M A GendooCentre for Computational Biology, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham B15 2SY, United Kingdom.ORCID 0000-0001-8891-4138
Eldad ZacksenhausToronto General Research Institute, University Health Network, Toronto, Ontario M5G 1L7, Canada.
Raya SaabDepartment of Pediatric and Adolescent Medicine, American University of Beirut, Beirut 1107 2020, Lebanon.
Pierre KhoueiryDepartment of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Beirut 1107 2020, Lebanon; pk17@aub.edu.lb.ORCID 0000-0001-7643-3310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric pineoblastomas (PBs) are rare and aggressive tumors of grade IV histology. Although some oncogenic drivers are characterized, including germline mutations in RB1 and DICER1, the role of epigenetic deregulation and

Indexed as

Brain NeoplasmsPineal GlandPinealomaAnimalsChildChromatinDEAD-box RNA HelicasesEnhancer Elements, GeneticHistonesHumansMiceRibonuclease IIIChromatinDEAD-box RNA HelicasesDICER1 protein, humanHistonesRibonuclease III

Identifiers

PMID36650051
PMCPMC10069464

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.