Evidence map›Paper›PMID 36649805›Full record

ArticleJournal of vascular and interventional radiology : JVIR2023

Preoperative Embolization of Metastatic Spinal Cord Compression with n-Butyl Cyanoacrylate: Safety and Effectiveness in Limiting Blood Loss.

Eslam Youssef, Ernesto Santos, Amgad M Moussa, Eric Lis, Maksim Vaynrub, Ori Barzilai, Mark Bilsky, Francois H Cornelis

Open access · greenAbstract read
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Refinement of nBCA embolization technique in treatment of metastatic spinal tumors: Case series and technical report.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eslam YoussefInterventional Radiology Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Ernesto SantosInterventional Radiology Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Amgad M MoussaInterventional Radiology Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Eric LisInterventional Radiology Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Maksim VaynrubDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Ori BarzilaiDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Mark BilskyDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Francois H CornelisInterventional Radiology Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: cornelif@mskcc.org.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeTo evaluate the safety and effectiveness of preoperative embolization with n-butyl cyanoacrylate (nBCA) performed for metastatic spinal cord compression (MSCC) in limiting blood loss (BL). MATERIALS AND

methodsIn this institutional review board-approved retrospective study, clinical records from 2017 to 2022 were reviewed. Twenty consecutive patients (11 men and 9 women; mean age, 65.8 years ± 10.0; range, 45-82 years) underwent 21 preoperative spine tumor embolizations with nBCA. Angiograms were used to calculate the percentage reduction in tumor vascularity, and relevant clinical data (levels studied and embolized, fluoroscopy time [FT], reference dose [RD], and Kerma area product [KAP]) and operative data (BL and operative time [OT]) were analyzed. Adverse events and outcomes were recorded.

resultsA median of 2 levels were embolized per procedure (range, 1-5) but 4.9 were studied (range, 1-10). After embolization, tumor blush was reduced by a median of 87.3% (range, 50%-90%). The mean FT was 41 minutes ± 15.4 (range, 16-67 minutes), the mean RD was 1,977.1 mGy ± 1,794.3 (range, 450.2-6,319 mGy), and the mean KAP was 180.5 Gy·cm

conclusionsPreoperative embolization of tumors resected for MSCC with nBCA is a safe procedure allowing for performance of surgery with acceptable BL.

Indexed as

Embolization, TherapeuticEnbucrilateSpinal Cord CompressionAgedBlood Loss, SurgicalFemaleHumansMaleRetrospective StudiesTreatment OutcomeEnbucrilate

Identifiers

PMID36649805
PMCPMC10065907
OpenAlexW4316126928

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.