Evidence map›Paper›PMID 36649459›Full record

ArticleEC microbiology2021

Coinfection of HIV-1 with

Lucas Banze, Ana Carina Madureira, Borges Cerveja Zacarias, Noémia Nhacupe, Carmen Mascaro-Lazcano, Constance A Benson, Robert T Schooley, Emilia Virginia Noormahomed

Open access · greenAbstract read
In one paragraph

Article in EC microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Lucas BanzeDepartment of Microbiology, Parasitology Laboratory, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Ana Carina MadureiraMozambique Institute for Health Education and Research, Maputo, Mozambique.
Borges Cerveja ZacariasDepartment of Microbiology, Parasitology Laboratory, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Noémia NhacupeDepartment of Microbiology, Parasitology Laboratory, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Carmen Mascaro-LazcanoDepartment of Parasitology, Universidad de Granada, Granada, Spain.
Constance A BensonDepartment of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego, USA.
Robert T SchooleyDepartment of Medicine, Infectious Diseases Division, University of California, San Diego, USA.
Emilia Virginia NoormahomedDepartment of Microbiology, Parasitology Laboratory, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Eduardo Mondlane University · MZUniversidad de Granada · ESUniversity of California, San Diego · US

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUSAN JANET LITTLE · 1994 to 2026
$78.4M
The University Eduardo Mondlane/UCSD Health-Professional Education Partnership InitiativeR25TW011216 · FIC · EDUARDO MONDLANE UNIVERSITY · PI NOORMAHOMED, EMILIA VIRGINIA · 2018 to 2022
$3.2M
Enhanced Advanced Biomedical Research Training for MozambiqueD43TW010135 · FIC · EDUARDO MONDLANE UNIVERSITY · PI NOORMAHOMED, EMILIA VIRGINIA · 2015 to 2019
$3.2M
FIC NIH HHS D43 TW010135FIC NIH HHS R25 TW011216NCATS NIH HHS UL1 TR001442NIAID NIH HHS P30 AI036214
6 · The paper itself

Abstract

Background: It is hypothesized that schistosomiasis and intestinal parasites increase susceptibility to HIV-1 infection and enhance AIDS progression by immunomodulation. This study aims to compare the prevalence and risk factors for schistosomiasis and intestinal parasites in HIV-1 infected and uninfected persons and to evaluate the association between HIV-1 induced immunosuppression and risk factors for parasite infection. Methods: This was a cross-sectional study conducted at Boane Health Center in Boane village, Maputo Province from April to June 2017 in 280 patients aged over 5 years. From each of 140 HIV-1 infected or 140 HIV-1 uninfected persons, demographic and clinical data were collected as well as one stool and urine sample for parasitological analysis. All stool samples were processed using direct wet mount and Ritchie method for detection of common parasites, and modified Ziehl-Neelsen staining techniques to identify Results: The overall prevalence of parasitism in the study population was 46.8% (131/280). Fifty six percent of the HIV-1 infected persons (78/140) were infected by at least one parasite compared to 38% (53/140 of the HIV-1 uninfected persons (odds ratio [OR] 2.0, 95% confidence interval [CI] 1.2-3.3).Further, HIV-1 infected persons were more likely to be infected by Conclusions: It is possible that the a high prevalence of schistosomiais and intestinal parasites in this region plays an important role on the transmission and pathogenesis of HIV.

Indexed as

Co-Infection HIV-1 And Schistosoma HaematobiumCo-Infection HIV-1 And Schistosoma MansoniEnteroparasitesIntestinal ParasitesMozambiqueNeglected Tropical DiseasesSynergism HIV-1 And ParasitismWater Born Parasites

Identifiers

PMID36649459
PMCPMC9836084
OpenAlexW4317358881

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.