Evidence map›Paper›PMID 36649435›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Molecular understanding of Ni

Eesha Khare, Seth Allen Cazzell, Jake Song, Niels Holten-Andersen, Markus J Buehler

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eesha KhareDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0001-8696-9821
Seth Allen CazzellDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0001-6220-0436
Jake SongDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0003-1254-6206
Niels Holten-AndersenDepartment of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
Markus J BuehlerLaboratory for Atomistic and Molecular Mechanics, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0002-4173-9659

Funding

Models to Predict Protein Biomaterial PerformanceU01EB014976 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI BUEHLER, MARKUS J., KAPLAN, DAVID L. · 2012 to 2020
$5.2M
Strain Analysis Software for Open ScienceR01AR077793 · NIAMS · WASHINGTON UNIVERSITY · PI Guy M Genin, Stavros Thomopoulos · 2020 to 2026
$5.2M
NIAMS NIH HHS R01 AR077793NIBIB NIH HHS U01 EB014976
6 · The paper itself

Abstract

Incorporating dynamic metal-coordination bonds as cross-links into synthetic materials has become attractive not only to improve self-healing and toughness, but also due to the tunability of metal-coordination bonds. However, a priori determination of bond lifetime of metal-coordination complexes, especially important in the rational design of metal-coordinated materials with prescribed properties, is missing. We report an empirical relationship between the energy landscape of metal-coordination bonds, simulated via metadynamics, and the resulting macroscopic relaxation time in ideal metal-coordinated hydrogels. Importantly, we expand the Arrhenius relationship between the macroscopic hydrogel relaxation time and metal-coordinate bond activation energy to include width and landscape ruggedness identified in the simulated energy landscapes. Using biologically relevant Ni

Indexed as

Coordination ComplexesHydrogelsMetalsCoordination ComplexesHydrogelsMetals

Identifiers

PMID36649435
PMCPMC9942824

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.