ArticlePloS one2023
Gender differences in dry eye disease symptoms associated with psychological health indicators among adults using mobile mental health apps.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Human meibomian gland organoids to study epithelial homeostasis and dysfunction.Protein & cell · 2026Article
- A comprehensive analysis of dry eye disease clinical trials (2000-2024): research trends and gaps.Frontiers in pharmacology · 2026Article
- Mental health burden associated with specific ocular conditions among Medicare Advantage beneficiaries with type 2 diabetes: examining the impact of glaucoma, cataracts, retinopathy, and dry eye on unhealthy mental health days.Frontiers in public health · 2026Article
- The Association Between Dry Eye Disease Symptoms, Digital Device Types, and Screen Distance Among Health Science Students: A Survey-Based Study.Health science reports · 2025Article
- The Clinical Value of the Ferning Test in Monitoring Dry Eye Syndrome in Patients with Sarcoidosis.Life (Basel, Switzerland) · 2025Article
- Observational Clinical Investigation Evaluating an Ophthalmic Solution Containing Xanthan Gum and Low Concentration Desonide Phosphate in Dry Eye Disease Treatment.Ophthalmology and therapy · 2024Article
- The PRAMOS Study: PRostaglandin Analogues Monotherapy-Awareness Survey on Ocular Surface Involvement.Ophthalmology and therapy · 2024Article
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to investigate the association between dry eye disease (DED) symptoms and mental health among Korean adults in the community.
methodsA cross-sectional study analyzed the data of 152 participants using mobile-phone applications for recording mental health. We defined individuals with DED symptoms as those who experienced a sense of irritation or dryness of the eye (either constantly or often). Mental health (perceived stress, depression, and anxiety) was assessed using the Perceived Stress Scale, Patient Health Questionnaire-9, and General Anxiety Disorder-7, in this order. Multiple logistic regression analysis was conducted to examine the association between DED symptoms and mental health. We also adjusted for possible covariates. We investigated sex differences in mental health status in relation to DED.
resultsWe found that 41.4% of the participants (48.4% female and 30.5% male) showed DED symptoms, and its prevalence was higher in female than in male. The average perceived stress and anxiety symptoms in the female with DED (24.69±4.73 and 6.56±5.09, respectively) were significantly higher than those without DED (21.38±4.68 and 4.54±4.03) (p = 0.020 and 0.038, respectively). Even after adjusting for possible covariates, female who had DED showed higher risks of perceived stress (OR = 1.28), depression (OR = 2.64), and anxiety (OR = 5.81).
conclusionsClinicians and nurses should therefore be aware of the possibility of mental health problems among female with DED.
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