Evidence map›Paper›PMID 36648994›Full record

ArticleTomography (Ann Arbor, Mich.)2022

Measurement of Charge and Refractive Indices in Optically Trapped and Ionized Living Cells.

Endris Muhammed, Daniel B Erenso, Ying Gao, Li Chen, Michele Kelley, Carina Vazquez, Mitchell Gale, Cody Nichols, Horace T Crogman

Abstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Endris MuhammedDepartment of Physics, Addis Ababa University, Addis Ababa 1176, Ethiopia.ORCID 0000-0001-8673-2752
Daniel B ErensoDepartment of Physics, Middle Tennessee State University, Murfreesboro, TN 37132, USA.
Ying GaoDepartment of Biology, Middle Tennessee State University, Murfreesboro, TN 37132, USA.
Li ChenDepartment of Biology, Middle Tennessee State University, Murfreesboro, TN 37132, USA.
Michele KelleyDepartment of Physics, Middle Tennessee State University, Murfreesboro, TN 37132, USA.
Carina VazquezDepartment of Physics, Middle Tennessee State University, Murfreesboro, TN 37132, USA.
Mitchell GaleDepartment of Physics, Middle Tennessee State University, Murfreesboro, TN 37132, USA.
Cody NicholsDepartment of Physics, California State University Dominguez Hills, Carson, CA 90747, USA.
Horace T CrogmanDepartment of Physics, California State University Dominguez Hills, Carson, CA 90747, USA.ORCID 0000-0003-3836-3707

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The post-ionization dynamics of chemo-treated and untreated 4T1 breast cancer cells ionized by laser trapping techniques are studied. We have determined each cell's charge and refractive index by developing a theoretical model for the forces determining the post-ionization dynamics. The shift in a cell's refractive index due to an intense oscillating electric field was studied, and the results are reported here. We observed that a trapped cell, as it becomes charged, will eventually exit the trap perpendicular to the beam's direction; this means that the electric force of the cell overcomes the trapping force. As a result, the cell's conductivity changes due to the oscillating field, causing a decrease in the cell's refractive index.

Indexed as

Models, TheoreticalRefractometrybreast cancer cellscell mechanicschemotherapylaser trappingradiotherapy

Identifiers

PMID36648994
PMCPMC9844322

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.