Evidence map›Paper›PMID 36648972›Full record

ReviewNeurology international2023

Copeptin Implementation on Stroke Prognosis.

Stella Karatzetzou, Dimitrios Tsiptsios, Anastasia Sousanidou, Styliani Fotiadou, Foteini Christidi, Christos Kokkotis, Aimilios Gkantzios, Eleftherios Stefas, Pinelopi Vlotinou, Antonia Kaltsatou and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Neurology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Copeptin as a promising biomarker of cerebrovascular events: A minireview.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Stella KaratzetzouNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Dimitrios TsiptsiosNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-1601-8788
Anastasia SousanidouNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-2092-6313
Styliani FotiadouNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0001-9819-4824
Foteini ChristidiNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Christos KokkotisDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, Greece.
Aimilios GkantziosNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-0890-4069
Eleftherios StefasNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Pinelopi VlotinouNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-8828-9093
Antonia KaltsatouFAME Laboratory, Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece.ORCID 0000-0003-2610-4900
Nikolaos AggelousisDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, Greece.ORCID 0000-0001-5108-7335
Konstantinos VadikoliasNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-0484-369X
Democritus University of Thrace · GRUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Predicting functional outcome following stroke is considered to be of key importance in an attempt to optimize overall stroke care. Although clinical prognostic tools have been widely implemented, optimal blood biomarkers might be able to yield additional information regarding each stroke survivor's propensity for recovery. Copeptin seems to have interesting prognostic potential poststroke. The present review aims to explore the prognostic significance of copeptin in stroke patients. Literature research of two databases (MEDLINE and Scopus) was conducted to trace all relevant studies published between 16 February 2012 and 16 February 2022 that focused on the utility of copeptin as a prognostic marker in acute stroke setting. 25 studies have been identified and included in the present review. The predictive ability of copeptin regarding both functional outcome and mortality appears to be in the range of established clinical variables, thus highlighting the added value of copeptin evaluation in stroke management. Apart from acute ischemic stroke, the discriminatory accuracy of the biomarker was also demonstrated among patients with transient ischemic attack, intracerebral hemorrhage, and subarachnoid hemorrhage. Overall, copeptin represents a powerful prognostic tool, the clinical implementation of which is expected to significantly facilitate the individualized management of stroke patients.

Indexed as

blood biomarkercerebrovascular diseasecopeptinprognosisrecoverystroke

Identifiers

PMID36648972
PMCPMC9844286
OpenAlexW4316928654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.