Evidence map›Paper›PMID 36648956›Full record

ArticleMethods and protocols2023

Efficacy and Long-Term Safety of Ibuprofen Gargle for Oral Lichen Planus: A Study Protocol of Randomized Crossover and Long-Term Extension Trials.

Yumi Kitahiro, Takeshi Ioroi, Yasumasa Kakei, Junya Yamashita, Akira Kimoto, Takumi Hasegawa, Asami Morioka, Kazuhiro Yamamoto, Masaya Akashi, Ikuko Yano

Open access · goldAbstract read
In one paragraph

Article in Methods and protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yumi KitahiroDepartment of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Kobe 650-0017, Japan.ORCID 0000-0002-0263-5726
Takeshi IoroiDepartment of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Kobe 650-0017, Japan.ORCID 0000-0002-9064-5106
Yasumasa KakeiDepartment of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Kobe 650-0017, Japan.ORCID 0000-0002-5997-514X
Junya YamashitaDepartment of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Kobe 650-0017, Japan.
Akira KimotoDepartment of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Kobe 650-0017, Japan.
Takumi HasegawaDepartment of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Kobe 650-0017, Japan.ORCID 0000-0002-7349-7084
Asami MoriokaDepartment of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Kobe 650-0017, Japan.
Kazuhiro YamamotoDepartment of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Kobe 650-0017, Japan.ORCID 0000-0002-7513-6725
Masaya AkashiDepartment of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Kobe 650-0017, Japan.
Ikuko YanoDepartment of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Kobe 650-0017, Japan.ORCID 0000-0001-9517-5628
Kobe University · JPKobe University Hospital · JP

Funding

Japan Society for the Promotion of Science 19K16413
6 · The paper itself

Abstract

Oral lichen planus (OLP) is a type of chronic and refractory stomatitis characterized by abnormal keratinization, which is often painful. There is no consensus regarding treatment options for OLP, particularly in the presence of pain. The current study protocol focuses on the short-term efficacy and long-term safety of an ibuprofen gargle for pain management in patients with OLP. Patients (

Indexed as

gargleibuprofenlong-term safetyone-arm clinical trialoral lichen planuspainrandomized crossover controlled trial

Identifiers

PMID36648956
PMCPMC9844393
OpenAlexW4315628320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.