Evidence map›Paper›PMID 36648917›Full record

ArticleGeriatrics (Basel, Switzerland)2023

Mini-Mental State Examination: Optimal Cut-Off Levels for Mild and Severe Cognitive Impairment.

Francesco Salis, Diego Costaggiu, Antonella Mandas

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Geriatrics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07016893 (Exercise Workshop, Skill-Based Art Approaches, and Awareness Studies for Elderly Individuals With Cognitive Impairment), which is not on this map. Cited by 81 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 5 pooled it
24.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07016893 nacompletednot on this mapstarted 2024, after this paper: background citation

Exercise Workshop, Skill-Based Art Approaches, and Awareness Studies for Elderly Individuals With Cognitive Impairment

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2024 to 2024Enrolled37ConditionsMild Cognitive Impairment (MCI), Dementia, Alzheimer Disease, Geriatric RehabilitationArmsHealthy aging interventions
3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 5 syntheses or guidelines pooled it, 109 citations in OpenAlex.

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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Francesco SalisDepartment of Medical Sciences, and Public Health, University of Cagliari, SS 554 Bvio Sestu, 09042 Monserrato, Italy.ORCID 0000-0002-4512-9161
Diego CostaggiuDepartment of Medical Sciences, and Public Health, University of Cagliari, SS 554 Bvio Sestu, 09042 Monserrato, Italy.
Antonella MandasDepartment of Medical Sciences, and Public Health, University of Cagliari, SS 554 Bvio Sestu, 09042 Monserrato, Italy.
University of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considering the need to intercept neurocognitive damage as soon as possible, it would be useful to extend cognitive test screening throughout the population. Here, we propose differential cut-off levels that can be used to identify mild and severe cognitive impairment with a simple and widely used first-level neurocognitive screening test: the Mini-Mental State Examination (MMSE). We studied a population of 262 patients referred for cognitive impairment testing using the MMSE and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), a neuropsychological battery. The sample consisted of 262 participants with mean age 73.8 years (60-87), of whom 154 (58.8%) women. No significant gender-related differences in cognitive ability were identified. The two tests (MMSE and RBANS) showed a moderate correlation in identifying cognitive deficit. We used RBANS as a categorial variable to identify different degrees of cognitive impairment. Youden's J indexes were used to consider the better sensitivity/specificity balance in the 24-point cut-off score for severe cognitive deficit, 29.7-point score for mild cognitive deficit, and 26.1-point score for both mild and severe cognitive deficit. The study shows that the MMSE does not identify early cognitive impairment. Though different cut-offs are needed to discriminate different impairment degrees, the 26.1-point score seems to be preferable to the others.

Indexed as

dementiamemorymild cognitive impairment (MCI)Mini-Mental State Examination (MMSE)Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)screening

Identifiers

PMID36648917
PMCPMC9844353
OpenAlexW4315786458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.